The need for new antifungal agents is undeniable. Current therapeutic choices for the
treatment of invasive fungal infections are limited to three classes of drugs. Most used …

In recent years, there has been a growing interest in researching and developing new
antimicrobial agents from various sources to combat microbial resistance. Therefore, a …

Invasive, life-threatening fungal infections are an important cause of morbidity and mortality,
particularly for patients with compromised immune function. The number of therapeutic …

Nanotechnology has the ability to improve human health with novel tools for the treatment of
diseases. In this study, Rothia endophytica is a novel endophytic bacterial strain isolated …

The synthesis of metal nanoparticles using plant extracts is a very promising method in
green synthesis. The medicinal value of Moringa oleifera leaves and the antimicrobial …

The increase of many deadly diseases like infections by multidrug-resistant bacteria implies
re-inventing the wheel on drug discovery. A better comprehension of the metabolisms and …

Highlights•Natural products are discovered through top-down and bottom-up
approaches.•Diverse sampling provides diverse natural products.•Powerful analytical …

Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Drug discovery from marine natural products has experienced a revival since the beginning
of this century. To be successful in this field, rapid dereplication (identification of already …

Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of
people with cystic fibrosis and is one of the most common causes of infectious-disease …