Recent advances in micro reaction technology

C Wiles, P Watts - Chemical Communications, 2011 - pubs.rsc.org
It is the intention of this review to provide the reader with a survey of the current literature
pertaining to the use of micro reactors in synthetic chemistry; recent advances are briefly …

Epihalohydrins in organic synthesis

GS Singh, K Mollet, M D'hooghe… - Chemical Reviews, 2013 - ACS Publications
Epihalohydrins [2-(halomethyl) oxiranes, 1, 2-epoxy-3-halopropanes](Figure 1) are well-
known versatile synthons and important reagents in the realm of organic synthesis …

Configurable 3D-Printed millifluidic and microfluidic 'lab on a chip'reactionware devices

PJ Kitson, MH Rosnes, V Sans, V Dragone, L Cronin - Lab on a Chip, 2012 - pubs.rsc.org
We utilise 3D design and 3D printing techniques to fabricate a number of miniaturised fluidic
'reactionware'devices for chemical syntheses in just a few hours, using inexpensive …

Continuous flow organic synthesis under high‐temperature/pressure conditions

T Razzaq, CO Kappe - Chemistry–An Asian Journal, 2010 - Wiley Online Library
Microreactor technology and continuous flow processing in general are key features in
making organic synthesis both more economical and environmentally friendly. When …

The microwave‐to‐flow paradigm: translating high‐temperature batch microwave chemistry to scalable continuous‐flow processes

TN Glasnov, CO Kappe - Chemistry–A European Journal, 2011 - Wiley Online Library
The popularity of dedicated microwave reactors in many academic and industrial
laboratories has produced a plethora of synthetic protocols that are based on this enabling …

[HTML][HTML] 3D-printed devices for continuous-flow organic chemistry

V Dragone, V Sans, MH Rosnes… - Beilstein journal of …, 2013 - beilstein-journals.org
We present a study in which the versatility of 3D-printing is combined with the processing
advantages of flow chemistry for the synthesis of organic compounds. Robust and …

KMnO4-Mediated Oxidation as a Continuous Flow Process

J Sedelmeier, SV Ley, IR Baxendale… - Organic letters, 2010 - ACS Publications
An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids
and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using …

[图书][B] Chemicals and fuels from bio-based building blocks

F Cavani, S Albonetti, F Basile, A Gandini - 2016 - books.google.com
An up-to-date and two volume overview of recent developments in the field of
chemocatalytic and enzymatic processes for the transformation of renewable material into …

[HTML][HTML] Rapid and efficient trifluoromethylation of aromatic and heteroaromatic compounds using potassium trifluoroacetate enabled by a flow system

M Chen, SL Buchwald - Angewandte Chemie (International ed. in …, 2013 - ncbi.nlm.nih.gov
The trifluoromethylation of aryl/heteroaryl iodides has been demonstrated using a flow
system, enabling a rapid rate of reaction. A broad spectrum of trifluoromethylated …

A flow-based synthesis of Imatinib: the API of Gleevec

MD Hopkin, IR Baxendale, SV Ley - Chemical communications, 2010 - pubs.rsc.org
A concise, flow-based synthesis of Imatinib, a compound used for the treatment of chronic
myeloid leukaemia, is described whereby all steps are conducted in tubular flow coils or …