Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand
Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …
Lactoferrin from milk: Nutraceutical and pharmacological properties
Lactoferrin is an iron-binding protein present in large quantities in colostrum and in breast
milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function …
milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function …
Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)
S Kumari, SM Ahsan, JM Kumar, AK Kondapi… - Scientific reports, 2017 - nature.com
Targeted delivery of drugs to the brain is challenging due to the restricted permeability
across the blood brain barrier (BBB). Gliomas are devastating cancers and their positive …
across the blood brain barrier (BBB). Gliomas are devastating cancers and their positive …
Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications
Lactoferrin (LF) is a naturally glycoprotein with iron-binding properties and diverse biological
applications including; antiviral, anti-inflammatory, antioxidant, anti-cancer and immune …
applications including; antiviral, anti-inflammatory, antioxidant, anti-cancer and immune …
Lactoferrin-and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy
J Zhang, X Xiao, J Zhu, Z Gao, X Lai… - International journal of …, 2018 - Taylor & Francis
Purpose Glioblastoma multiforme (GBM) is the most common malignant brain tumor
originating in the central nervous system in adults. Based on nanotechnology such as …
originating in the central nervous system in adults. Based on nanotechnology such as …
Chemical conjugation in drug delivery systems
Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer
are usually so intense and invasive that they weaken the patient to cure as dangerous as the …
are usually so intense and invasive that they weaken the patient to cure as dangerous as the …
Brain targeted delivery of carmustine using solid lipid nanoparticles modified with tamoxifen and lactoferrin for antitumor proliferation
YC Kuo, SJ Cheng - International journal of pharmaceutics, 2016 - Elsevier
Solid lipid nanoparticles (SLNs) conjugated with tamoxifen (TX) and lactoferrin (Lf) were
applied to carry anticancer carmustine (BCNU) across the blood–brain barrier (BBB) for …
applied to carry anticancer carmustine (BCNU) across the blood–brain barrier (BBB) for …
Nanoformulation of lactoferrin potentiates its activity and enhances novel biotechnological applications
EM El-Fakharany - International Journal of Biological Macromolecules, 2020 - Elsevier
Lactoferrin is a glycoprotein with a molecular weight of 80 kDa, which produced in many
mammalian excretions. LF is involved in various physiological processes and known to …
mammalian excretions. LF is involved in various physiological processes and known to …
[HTML][HTML] Biomedical applications of lactoferrin on the ocular surface
U Regueiro, M López-López, R Varela-Fernández… - Pharmaceutics, 2023 - mdpi.com
Lactoferrin (LF) is a first-line defense protein with a pleiotropic functional pattern that
includes anti-inflammatory, immunomodulatory, antiviral, antibacterial, and antitumoral …
includes anti-inflammatory, immunomodulatory, antiviral, antibacterial, and antitumoral …
Gastrointestinally absorbable lactoferrin-heparin conjugate with anti-angiogenic activity for treatment of brain tumor
Glioblastoma multiforme (GBM) is a central nervous system disease with poor prognosis.
Curative treatments for GBM involve chemotherapy, radiotherapy, and surgical pathways …
Curative treatments for GBM involve chemotherapy, radiotherapy, and surgical pathways …