Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome

J Wang, D Wu, H Guo, M Li - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is one of the most common systemic reproductive
endocrine diseases, which has a variety of effects on a woman's health. Because of the …

Resistance to the insulin and elevated level of androgen: A major cause of polycystic ovary syndrome

H Ding, J Zhang, F Zhang, S Zhang, X Chen… - Frontiers in …, 2021 - frontiersin.org
PCOS has a wide range of negative impacts on women's health and is one of the most
frequent reproductive systemic endocrine disorders. PCOS has complex characteristics and …

Targeting autophagy in obesity: from pathophysiology to management

Y Zhang, JR Sowers, J Ren - Nature Reviews Endocrinology, 2018 - nature.com
Obesity poses a severe threat to human health, including the increased prevalence of
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …

Androgen sensitivity gateway to COVID‐19 disease severity

CG Wambier, A Goren, S Vaño‐Galván… - Drug development …, 2020 - Wiley Online Library
In this communication, we present arguments for androgen sensitivity as a likely determinant
of COVID‐19 disease severity. The androgen sensitivity model explains why males are more …

Polycystic ovary syndrome and infertility: an update

M Zehravi, M Maqbool, I Ara - International journal of adolescent …, 2022 - degruyter.com
Polycystic ovarian syndrome is the most well-known endocrine condition among women of
this generation (PCOS). Symptoms of hyperandrogenism, irregular menstrual periods, and …

A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS)

A Moini Jazani, H Nasimi Doost Azgomi… - DARU Journal of …, 2019 - Springer
Background Polycystic ovary syndrome (PCOS) is a frequent medical condition
characterized by both metabolic and reproductive disorders. Different pharmaceutical …

[HTML][HTML] Prevalence of polycystic ovarian syndrome in India: a systematic review and meta-analysis

MD Bharali, R Rajendran, J Goswami, K Singal… - Cureus, 2022 - ncbi.nlm.nih.gov
Stein-Leventhal syndrome, often known as polycystic ovarian syndrome (PCOS), is a
syndrome that affects women's reproductive health. PCOS is one of the most common …

[HTML][HTML] Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication

M Chen, C He, K Zhu, Z Chen, Z Meng, X Jiang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Polycystic ovary syndrome (PCOS) is closely linked to follicular dysplasia and
impaired bidirectional oocyte-granulosa cell (GC) communication. Given that PCOS is a …

Efficacy and safety of anti-androgens in the management of polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials

S Alesi, M Forslund, J Melin, D Romualdi, A Peña… - …, 2023 - thelancet.com
Background Anti-androgens and combined oral contraceptive pills (COCPs) may mitigate
hyperandrogenism-related symptoms of polycystic ovary syndrome (PCOS). However, their …

Follicular fluid: a powerful tool for the understanding and diagnosis of polycystic ovary syndrome

AT Brinca, AC Ramalhinho, Â Sousa, AH Oliani… - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …