The genomes of virtually all organisms contain repetitive sequences that are generated by
the activity of transposable elements (transposons). Transposons are mobile genetic …

As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …

The absolute reliance of the mammalian brain on oxygen to generate ATP renders it acutely
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …

Lifespan varies within and across species, but the general principles of its control remain
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …

Pacific Ocean rockfishes (genus Sebastes) exhibit extreme variation in life span, with some
species being among the most long-lived extant vertebrates. We de novo assembled the …

Upland cotton is a model for polyploid crop domestication and transgenic improvement.
Here we sequenced the allotetraploid Gossypium hirsutum L. acc. TM-1 genome by …

The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …

Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for …

The mammalian radiation has corresponded with rapid changes in noncoding regions of the
genome, but we lack a comprehensive understanding of regulatory evolution in mammals …

Although many de novo genome assembly projects have recently been conducted using
high-throughput sequencers, assembling highly heterozygous diploid genomes is a …