Molecular farming–the slope of enlightenment
Molecular farming can be defined as the use of plants to produce recombinant protein
products. The technology is now> 30 years old. The early promise of molecular farming was …
products. The technology is now> 30 years old. The early promise of molecular farming was …
Plant-based biopharmaceutical engineering
L Eidenberger, B Kogelmann… - Nature Reviews …, 2023 - nature.com
Plants can be engineered to recombinantly produce high-quality proteins such as
therapeutic proteins and vaccines, also known as molecular farming. Molecular farming can …
therapeutic proteins and vaccines, also known as molecular farming. Molecular farming can …
Plants as sources of natural and recombinant anti-cancer agents
JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …
pharmacologically active secondary metabolites produced by plants. Some of these …
CRISPR/Cas9‐mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β‐1,2‐xylose and …
Plants offer fast, flexible and easily scalable alternative platforms for the production of
pharmaceutical proteins, but differences between plant and mammalian N‐linked glycans …
pharmaceutical proteins, but differences between plant and mammalian N‐linked glycans …
Plant-produced biopharmaceuticals: a case of technical developments driving clinical deployment
GP Lomonossoff, MA D'Aoust - Science, 2016 - science.org
The ability to express heterologous proteins in plants has led to the concept of using plants
as “bioreactors” or “biofactories” for the production of pharmaceutical proteins. Although …
as “bioreactors” or “biofactories” for the production of pharmaceutical proteins. Although …
[HTML][HTML] Very-large-scale production of antibodies in plants: The biologization of manufacturing
Gene technology has facilitated the biologization of manufacturing, ie the use and
production of complex biological molecules and systems at an industrial scale. Monoclonal …
production of complex biological molecules and systems at an industrial scale. Monoclonal …
Plant molecular farming–integration and exploitation of side streams to achieve sustainable biomanufacturing
JF Buyel - Frontiers in plant science, 2019 - frontiersin.org
Plants have unique advantages over other systems such as mammalian cells for the
production of valuable small molecules and proteins. The benefits cited most often include …
production of valuable small molecules and proteins. The benefits cited most often include …
High level production of monoclonal antibodies using an optimized plant expression system
AG Diamos, JGL Hunter, MD Pardhe… - … in Bioengineering and …, 2020 - frontiersin.org
Biopharmaceuticals are a large and fast-growing sector of the total pharmaceutical market
with antibody-based therapeutics accounting for over 100 billion USD in sales yearly …
with antibody-based therapeutics accounting for over 100 billion USD in sales yearly …
Contributions of the international plant science community to the fight against human infectious diseases–part 1: epidemic and pandemic diseases
M Lobato Gomez, X Huang, D Alvarez… - Plant biotechnology …, 2021 - Wiley Online Library
Infectious diseases, also known as transmissible or communicable diseases, are caused by
pathogens or parasites that spread in communities by direct contact with infected individuals …
pathogens or parasites that spread in communities by direct contact with infected individuals …
Killer to cure: expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors
LA Ridgley, N Falci Finardi… - Plant Biotechnology …, 2023 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have achieved huge clinical success. However, many
still have limited response rates, and are prohibitively costly. There is a need for effective …
still have limited response rates, and are prohibitively costly. There is a need for effective …