The pathogenesis of any given human disease is a complex multifactorial process
characterized by many biologically significant and interdependent alterations. One of these …

Cancer is as much an epigenetic disease as it is a genetic disease, and epigenetic
alterations in cancer often serve as potent surrogates for genetic mutations. Normal …

Bisphenol-A (BPA) is a nonsteroidal estrogen that is ubiquitous in the environment. The
homeobox gene Hoxa10 controls uterine organogenesis, and its expression is affected by in …

Diethylstilbestrol (DES) is a nonsteroidal estrogen that induces developmental anomalies of
the female reproductive tract. The homeobox gene HOXA10 controls uterine organogenesis …

Abstract Treatment failure is one of the main hurdles in treating cervical cancer, despite
significant breakthroughs in both conventional and targeted therapy. The one-year survival …

Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …

Cancer is ranked as one of the top killers in all human diseases and continues to have a
devastating effect on the population around the globe. Current research efforts are aiming to …

Cervical cancer is the second most common cancer among women worldwide. About
528,000 women are diagnosed with cervical cancer contributing to around 266,000 deaths …

OBJECTIVE: The objective of the study was to evaluate the influence of genetic
polymorphisms of GSTM1, GSTT1, and GSTM3 on the susceptibility of cervical cancer …

The role of the cancer/testis antigen CAGE in drug resistance was investigated. The drug-
resistant human melanoma Malme3M (Malme3M R) and the human hepatic cancer cell line …