Traditional vaccines, based on the administration of killed or attenuated microorganisms,
have proven to be among the most effective methods for disease prevention. Safety issues …

Traditional vaccination approaches (eg live attenuated or killed microorganisms) are among
the most effective means to prevent the spread of infectious diseases. These approaches …

Dengue represents a major public health problem of growing global importance. In the
absence of specific dengue therapeutics, strategies for disease control have increasingly …

Dengue is currently the most significant arboviral disease afflicting tropical and sub-tropical
countries worldwide. Dengue vaccines, such as the multivalent attenuated, chimeric, DNA …

Dengue viruses are emerging mosquito-borne pathogens belonging to Flaviviridae family
which are transmitted to humans via the bites of infected mosquitoes Aedes aegypti and …

Novel and more effective immunization strategies against many animal diseases may profit
from the current knowledge on the modulation of specific immunity through stimulation of …

Dengue is one of the most important emerging vector-borne viral diseases. There are four
serotypes of dengue viruses (DENV), each of which is capable of causing self-limited …

Traditional vaccines derived from attenuated or inactivated pathogens are effective at
inducing antibody-based protective immune responses but tend to be highly reactogenic …

Subunit vaccines offer a means to produce safer, more defined vaccines compared to
traditional whole microorganism approaches. Subunit antigens, however, exhibit weak …

We developed a novel platform to express high levels of recombinant lipoproteins with
intrinsic adjuvant properties. Based on this technology, our group developed recombinant …