Retinal ischemia is a common cause of visual impairment and blindness. At the cellular
level, ischemic retinal injury consists of a self-reinforcing destructive cascade involving …

Management of glaucoma is directed at the control of intraocular pressure (IOP), yet it is
recognized now that increased IOP is just an important risk factor in glaucoma. Therapy that …

This book represents the first serious attempt to explain the fundamental basis of
ozonetherapy and is a relevant step towards achieving further progress. Ozone is now …

Elevated vascular endothelial growth factor (VEGF) levels are required for ocular and tumor
angiogenesis in animal models. Ischemic hypoxia is strongly correlated with increased …

PURPOSE: The protective effects of three survival-promoting agents on ischemia-induced
retinal injury in the rat were investigated. The agents included brain-derived neurotrophic …

Experimental evidence exists to suggest that zinc can have positive and negative effects on
the physiology of cells depending on the 'local'concentration, localisation (extracellular vs …

Reactive oxygen species (ROS) can be generated in biological tissues, including the retina,
in particular under or after ischemia. They can provoke cell necrosis by reacting with cell …

Contemporary concepts of open angle glaucoma suggest that the current emphasis on
reduction of elevated intraocular pressure could be augmented by other therapeutic …

On the basis that ozone (O3) can upregulate cellular antioxidant enzymes, a morphological,
biochemical and functional renal study was performed in rats undergoing a prolonged …

Purpose: Various protein contents such as enzymes, growth factors, and structural
components are responsible for biological activities in organs. We have created a map of …