Ferritin: a multifunctional nanoplatform for biological detection, imaging diagnosis, and drug delivery

N Song, J Zhang, J Zhai, J Hong, C Yuan… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Ferritins are spherical iron storage proteins within cells that are composed of a
combination of 24 subunits of two types, heavy-chain ferritin (HFn) and light-chain ferritin …

[HTML][HTML] Mesoporous silica nanoparticles in target drug delivery system: A review

C Bharti, U Nagaich, AK Pal, N Gulati - International journal of …, 2015 - ncbi.nlm.nih.gov
Due to lack of specification and solubility of drug molecules, patients have to take high
doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To …

Machine-learning-assisted single-vessel analysis of nanoparticle permeability in tumour vasculatures

M Zhu, J Zhuang, Z Li, Q Liu, R Zhao, Z Gao… - Nature …, 2023 - nature.com
The central dogma that nanoparticle delivery to tumours requires enhanced leakiness of
vasculatures is a topic of debate. To address this, we propose a single-vessel quantitative …

Multifunctional nanoparticles for multimodal imaging and theragnosis

DE Lee, H Koo, IC Sun, JH Ryu, K Kim… - Chemical Society …, 2012 - pubs.rsc.org
Nanomedicine is the biomedical application of nanoscale materials for diagnosis and
therapy of disease. Recent advances in nanotechnology and biotechnology have …

Biomineralization-inspired synthesis of copper sulfide–ferritin nanocages as cancer theranostics

Z Wang, P Huang, O Jacobson, Z Wang, Y Liu, L Lin… - ACS …, 2016 - ACS Publications
It is essential to control the size and morphology of nanoparticles strictly in nanomedicine.
Protein cages offer significant potential for templated synthesis of inorganic nanoparticles. In …

H-ferritin–nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection

M Liang, K Fan, M Zhou, D Duan… - Proceedings of the …, 2014 - National Acad Sciences
An ideal nanocarrier for efficient drug delivery must be able to target specific cells and carry
high doses of therapeutic drugs and should also exhibit optimized physicochemical …

Ferritin–a multifaceted protein scaffold for biotherapeutics

NK Lee, S Cho, IS Kim - Experimental & Molecular Medicine, 2022 - nature.com
The ferritin nanocage is an endogenous protein that exists in almost all mammals. Its hollow
spherical structure that naturally stores iron ions has been diversely exploited by …

Magnetoferritin nanoparticles for targeting and visualizing tumour tissues

K Fan, C Cao, Y Pan, D Lu, D Yang, J Feng… - Nature …, 2012 - nature.com
Engineered nanoparticles have been used to provide diagnostic,,, therapeutic, and
prognostic information, about the status of disease. Nanoparticles developed for these …

Bioengineered bacterial outer membrane vesicles as cell-specific drug-delivery vehicles for cancer therapy

V Gujrati, S Kim, SH Kim, JJ Min, HE Choy, SC Kim… - ACS …, 2014 - ACS Publications
Advances in genetic engineering tools have contributed to the development of strategies for
utilizing biologically derived vesicles as nanomedicines for achieving cell-specific drug …

Multifunctional nanoparticles for drug delivery and molecular imaging

G Bao, S Mitragotri, S Tong - Annual review of biomedical …, 2013 - annualreviews.org
Recent advances in nanotechnology and growing needs in biomedical applications have
driven the development of multifunctional nanoparticles. These nanoparticles, through …