In recent years, the relationship between Cyp2C19* 2 gene polymorphism and clopidogrel
resistance reflected by platelet function assay has been studied extensively, but there is no …

Background Coronary artery disease (CAD) is the most common reason for mortality and
disability-adjusted life years (DALYs) lost globally. This study aimed to suggest a new gene …

Background: High on-treatment platelet reactivity (HTPR) has been suggested as a risk
factor for patients with ischemic vascular disease. We explored a predictive model of platelet …

The morbidity of coronary artery disease (CAD) in the Uygur population of Xinjiang was
much higher than the national average. Clopidogrel is the most commonly used medication …

Background The present study aimed at examining the inhibitory effect of two atypical
neuroleptics iloperidone and lurasidone on the main human cytochrome P450 (CYP) …

Abstract Background CYP2C19* 17 (rs12248560) is a functional single nucleotide
polymorphism (SNP) in the CYP2C19 gene. It has been shown that CYP2C19* 17 is …

Background Pharmacogenomics is a branch of biotechnological science integrating
medicine, pharmacology, and genomics techniques. Moreover, it focuses on creating drug …

Coronary artery disease (CAD) has a high mortality rate. Despite various therapeutic targets,
non-responsiveness to drugs remains a prevalent issue. Pharmacogenomics assesses the …

OBJECTIVE: Human cytochrome p450 enzymes play an important role in the metabolism of
various substances. The CYP2C subfamily consists of various important drug-metabolizing …

Antiplatelet therapy is the foundational treatment for the prevention and treatment of
coronary and cerebrovascular ischemic events in patients with coronary heart disease …