Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Prohibitins (PHBs) are a class of highly evolutionarily conserved proteins that widely
distribute in prokaryotes and eukaryotes. PHBs function in cell growth and proliferation or …

Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with
potential applications during all stages of patient care, from diagnosis to long-term follow-up …

Every year, approximately 600 infants, children, and adolescents are diagnosed with renal
cancer in the United States. In addition to Wilms tumor (WT), which accounts for about 80 …

Background The underlying mechanism involved in ovarian cancer stemness and
chemoresistance remains largely unknown. Here, we explored whether the regulation of c …

Wilms tumor (WT), or nephroblastoma, is the predominant renal malignancy in the pediatric
population. This narrative review explores the evolution of personalized care strategies for …

The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred
Knudson proposed the 'two-hit'model of tumour development. Since then, the efforts of …

Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

Objective: To investigate the effect of ethyl acetate extract from Celastrus orbiculatus (COE)
on gastric cancer cell apoptosis and reveal its underlying molecular mechanism. In addition …

Characterisation of histological, immunohistochemical and molecular prognostic and
predictive biomarkers has contributed significantly to precision medicine and better …