Beyond autophagy: LC3-associated phagocytosis and endocytosis
C Peña-Martinez, AD Rickman, BL Heckmann - Science advances, 2022 - science.org
Noncanonical functions of the autophagy machinery in pathways including LC3-associated
phagocytosis and LC3-associated endocytosis have garnered increasing interest in both …
phagocytosis and LC3-associated endocytosis have garnered increasing interest in both …
Mechanisms governing autophagosome biogenesis
H Nakatogawa - Nature reviews Molecular cell biology, 2020 - nature.com
Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
The molecular function of Atg9, the sole transmembrane protein in the autophagosome-
forming machinery, remains unknown. Atg9 colocalizes with Atg2 at the expanding edge of …
forming machinery, remains unknown. Atg9 colocalizes with Atg2 at the expanding edge of …
[HTML][HTML] ER as master regulator of membrane trafficking and organelle function
EM Wenzel, LA Elfmark, H Stenmark… - The Journal of cell …, 2022 - ncbi.nlm.nih.gov
The endoplasmic reticulum (ER), which occupies a large portion of the cytoplasm, is the
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …
The autophagic membrane tether ATG2A transfers lipids between membranes
An enigmatic step in de novo formation of the autophagosome membrane compartment is
the expansion of the precursor membrane phagophore, which requires the acquisition of …
the expansion of the precursor membrane phagophore, which requires the acquisition of …
Emerging roles of ATG proteins and membrane lipids in autophagosome formation
T Nishimura, SA Tooze - Cell discovery, 2020 - nature.com
Autophagosome biogenesis is a dynamic membrane event, which is executed by the
sequential function of autophagy-related (ATG) proteins. Upon autophagy induction, a cup …
sequential function of autophagy-related (ATG) proteins. Upon autophagy induction, a cup …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
LC3-associated phagocytosis and inflammation
Abstract LC3-associated phagocytosis (LAP) is a novel form of non-canonical autophagy
where LC3 (microtubule-associated protein 1A/1B–light chain 3) is conjugated to …
where LC3 (microtubule-associated protein 1A/1B–light chain 3) is conjugated to …
[HTML][HTML] Autophagosome maturation and fusion
F Reggiori, C Ungermann - Journal of molecular biology, 2017 - Elsevier
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic
components, including cytosol and organelles, to the lysosome in double-membrane …
components, including cytosol and organelles, to the lysosome in double-membrane …
WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome
T Proikas-Cezanne, Z Takacs, P Dönnes… - Journal of cell …, 2015 - journals.biologists.com
Autophagy is a pivotal cytoprotective process that secures cellular homeostasis, fulfills
essential roles in development, immunity and defence against pathogens, and determines …
essential roles in development, immunity and defence against pathogens, and determines …