Dietary options for rodents in the study of obesity

M Bastías-Pérez, D Serra, L Herrero - Nutrients, 2020 - mdpi.com
Obesity and its associated metabolic diseases are currently a priority research area. The
increase in global prevalence at different ages is having an enormous economic and health …

Recent update on the molecular mechanisms of gonadal steroids action in adipose tissue

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2021 - mdpi.com
The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Towards understanding the direct and indirect actions of growth hormone in controlling hepatocyte carbohydrate and lipid metabolism

MC Vázquez-Borrego, M del Rio-Moreno, RD Kineman - Cells, 2021 - mdpi.com
Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …

A neuroscientist's guide to the vole

WM Kenkel, ML Gustison, AK Beery - Current protocols, 2021 - Wiley Online Library
Prairie voles have emerged as an important rodent model for understanding the
neuroscience of social behavior. Prairie voles are well known for their capacity for pair …

Generation of mega brown adipose tissue in adults by controlling brown adipocyte differentiation in vivo

Q Du, J Wu, C Fischer, T Seki, X Jing… - Proceedings of the …, 2022 - National Acad Sciences
Brown adipose tissue (BAT) is a highly specialized adipose tissue in its immobile location
and size during the entire adulthood. In response to cold exposure and other β3 …

The Role and Regulatory Mechanism of Brown Adipose Tissue Activation in Diet-Induced Thermogenesis in Health and Diseases

PC Chan, PS Hsieh - International Journal of Molecular Sciences, 2022 - mdpi.com
Brown adipose tissue (BAT) has been considered a vital organ in response to non-shivering
adaptive thermogenesis, which could be activated during cold exposure through the …

miR-130b/301b is a negative regulator of beige adipogenesis and energy metabolism in vitro and in vivo

W Luo, Y Kim, ME Jensen, O Herlea-Pana, W Wang… - Diabetes, 2022 - Am Diabetes Assoc
Thermogenic brown or beige adipocytes dissipate energy in the form of heat and thereby
counteract obesity and related metabolic complications. The miRNA cluster miR-130b/301b …

[HTML][HTML] The evolving view of thermogenic fat and its implications in cancer and metabolic diseases

X Yin, Y Chen, R Ruze, R Xu, J Song… - Signal Transduction and …, 2022 - nature.com
The incidence of metabolism-related diseases like obesity and type 2 diabetes mellitus has
reached pandemic levels worldwide and increased gradually. Most of them are listed on the …

[HTML][HTML] Bone morphogenic protein 9 is a novel thermogenic hepatokine secreted in response to cold exposure

JH Um, SY Park, JH Hur, HY Lee, KH Jeong, Y Cho… - Metabolism, 2022 - Elsevier
Objective Maintaining a constant core body temperature is essential to homeothermic
vertebrate survival. Adaptive thermogenesis in brown adipose tissue and skeletal muscle is …

The exercise-instrumental music program and irisin levels in younger non-professional athletes

S Sugiharto, D Merawati… - Comparative …, 2022 - wageningenacademic.com
A passive lifestyle and lack of exercise are triggering factors in increasing metabolic
syndrome, whereas metabolic syndrome is associated with increased morbidity and …