Novel prediction equations for absolute risk assessment of total cardiovascular disease incorporating cardiovascular-kidney-metabolic health: a scientific statement …
Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …
the American Heart Association in response to the high prevalence of metabolic and kidney …
Coronary artery calcification: current concepts and clinical implications
C Onnis, R Virmani, K Kawai, V Nardi, A Lerman… - Circulation, 2024 - Am Heart Assoc
Coronary artery calcification (CAC) accompanies the development of advanced
atherosclerosis. Its role in atherosclerosis holds great interest because the presence and …
atherosclerosis. Its role in atherosclerosis holds great interest because the presence and …
Polygenic risk score associates with atherosclerotic plaque characteristics at autopsy
A Cornelissen, NV Gadhoke, K Ryan… - … , and vascular biology, 2024 - Am Heart Assoc
BACKGROUND: Polygenic risk scores (PRSs) for coronary artery disease (CAD) potentially
improve cardiovascular risk prediction. However, their relationship with histopathologic …
improve cardiovascular risk prediction. However, their relationship with histopathologic …
Personalization of Primary Prevention: Exploring the Role of Coronary Artery Calcium and Polygenic Risk Score in Cardiovascular Diseases
Personalized healthcare is becoming increasingly popular given the vast heterogeneity in
disease manifestation between individuals. Many commonly encountered diseases within …
disease manifestation between individuals. Many commonly encountered diseases within …
The science of precision prevention: Research opportunities and clinical applications to reduce cardiovascular health disparities
TA Pearson, D Vitalis, C Pratt, R Campo… - JACC: Advances, 2024 - jacc.org
Precision prevention embraces personalized prevention but includes broader factors such
as social determinants of health to improve cardiovascular health. The quality, quantity …
as social determinants of health to improve cardiovascular health. The quality, quantity …
Polygenic risk is associated with long-term coronary plaque progression and high-risk plaque
Background The longitudinal relation between coronary artery disease (CAD) polygenic risk
score (PRS) and long-term plaque progression and high-risk plaque (HRP) features is …
score (PRS) and long-term plaque progression and high-risk plaque (HRP) features is …
Factors predicting the recurrence of atrial fibrillation after catheter ablation: a review
D Mo, M Wang, P Zhang, H Dai, J Guan - Heliyon, 2024 - cell.com
Atrial fibrillation (AF) is the most common and clinically significant type of cardiac arrhythmia.
Although catheter ablation (CA) can restore sinus rhythm in patients with AF, some patients …
Although catheter ablation (CA) can restore sinus rhythm in patients with AF, some patients …
Predictive improvement of adding coronary calcium score and a genetic risk score to a traditional risk model for cardiovascular event prediction
M Temtem, MI Mendonça… - European Journal of …, 2024 - academic.oup.com
Aims Coronary artery calcium score (CACS) and polygenic risk score have been used as
novel markers to predict cardiovascular (CV) events of asymptomatic individuals compared …
novel markers to predict cardiovascular (CV) events of asymptomatic individuals compared …
Atherosclerotic cardiovascular disease risk prediction: current state-of-the-art
Cardiovascular disease (CVD) is the leading cause of mortality worldwide, resulting in~ 18
million deaths annually. 1 Atherosclerotic CVD (ASCVD) accounts for four out of every five …
million deaths annually. 1 Atherosclerotic CVD (ASCVD) accounts for four out of every five …
Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores
We construct non-linear machine learning (ML) prediction models for systolic and diastolic
blood pressure (SBP, DBP) using demographic and clinical variables and polygenic risk …
blood pressure (SBP, DBP) using demographic and clinical variables and polygenic risk …