A novel and compact review on the role of oxidative stress in female reproduction

J Lu, Z Wang, J Cao, Y Chen, Y Dong - Reproductive Biology and …, 2018 - Springer
In recent years, the study of oxidative stress (OS) has become increasingly popular. In
particular, the role of OS on female fertility is very important and has been focused on …

Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview

ES Ali, S Akter, S Ramproshad, B Mondal… - Cancer cell …, 2022 - Springer
MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase)
pathway is an important link in the transition from extracellular signals to intracellular …

Cardioprotective effects of alpha‐mangostin on doxorubicin‐induced cardiotoxicity in rats

F Eisvand, M Imenshahidi… - Phytotherapy …, 2022 - Wiley Online Library
The main adverse effect of doxorubicin is cardiotoxicity. Oxidative stress and apoptosis
induction have been suggested as mechanisms involved in its cardiotoxicity. In this study …

Green Biosynthesized Silver Nanoparticles With Aqueous Extracts of Ginkgo Biloba Induce Apoptosis via Mitochondrial Pathway in Cervical Cancer Cells

Z Xu, Q Feng, M Wang, H Zhao, Y Lin, S Zhou - Frontiers in oncology, 2020 - frontiersin.org
Biosynthetic silver nanoparticles (AgNPs), specifically formed using medicinal plant extracts,
have recently exhibited a remarkable therapeutic effect due to their anticancer potential …

The purple mangosteen (Garcinia mangostana): Defining the anticancer potential of selected xanthones

MC Nauman, JJ Johnson - Pharmacological research, 2022 - Elsevier
The purple mangosteen (Garcinia mangostana) is a popular Southeast Asian fruit that has
been used traditionally for its health promoting benefits for years. Unique to the mangosteen …

Neuroprotective effect of α-mangostin in ameliorating propionic acid-induced experimental model of autism in Wistar rats

A Tiwari, R Khera, S Rahi, S Mehan, HA Makeen… - Brain sciences, 2021 - mdpi.com
Several studies have documented the role of hyper-activation of extracellular signal-
regulated kinases (ERK) in Autism pathogenesis. Alpha-mangostin (AMG) is a …

Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …

Modulation of multiple signaling pathways of the plant-derived natural products in cancer

L Sun, W Zhou, H Zhang, Q Guo, W Yang, B Li… - Frontiers in …, 2019 - frontiersin.org
Natural compounds are highly effective anticancer chemotherapeutic agents, and the targets
of plant-derived anticancer agents have been widely reported. In this review, we focus on …

Nanoparticle drug delivery systems for α-mangostin

N Wathoni, A Rusdin, K Motoyama, IM Joni… - Nanotechnology …, 2020 - Taylor & Francis
Abstract α-Mangostin, a xanthone derivative from the pericarp of Garcinia mangostana L.,
has numerous bioactivities and pharmacological properties. However, α-mangostin has low …

[HTML][HTML] Biochemical features and therapeutic potential of α-Mangostin: Mechanism of action, medicinal values, and health benefits

M Alam, S Rashid, K Fatima, M Adnan, A Shafie… - Biomedicine & …, 2023 - Elsevier
Abstract α-Mangostin (α-MG) is a natural xanthone obtained from the pericarps of
mangosteen. It exhibits excellent potential, including anti-cancer, neuroprotective …