Cyclin-dependent kinase 4/6 inhibitors for cancer therapy: A patent review (2015–2019)

PF Wang, HY Qiu, Y He, HL Zhu - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
Introduction Cyclin-dependent kinases 4 and 6 (CDK4/6) along with their
upstream/downstream components are pivotal regulators for the cell cycle progression. The …

Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets

I Abdelbaky, H Tayara, KT Chong - Scientific Reports, 2021 - nature.com
Protein kinases are receiving wide research interest, from drug perspective, due to their
important roles in human body. Available kinase-inhibitor data, including crystallized …