Role of catalase in oxidative stress‐and age‐associated degenerative diseases

A Nandi, LJ Yan, CK Jana, N Das - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive species produced in the cell during normal cellular metabolism can chemically
react with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing …

The metal ion hypothesis of Alzheimer's disease and the anti-neuroinflammatory effect of metal chelators

LL Chen, YG Fan, LX Zhao, Q Zhang, ZY Wang - Bioorganic chemistry, 2023 - Elsevier
Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …

Role of copper in the onset of Alzheimer's disease compared to other metals

S Bagheri, R Squitti, T Haertlé, M Siotto… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by amyloid
plaques in patients' brain tissue. The plaques are mainly made of β-amyloid peptides and …

Copper toxicity links to pathogenesis of Alzheimer's disease and therapeutics approaches

HW Ejaz, W Wang, M Lang - International Journal of Molecular Sciences, 2020 - mdpi.com
Alzheimer's disease (AD) is an irreversible, age-related progressive neurological disorder,
and the most common type of dementia in aged people. Neuropathological lesions of AD …

Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds

SK Singh, S Srivastav, AK Yadav… - Oxidative medicine …, 2016 - Wiley Online Library
Alzheimer's disease (AD) is a complex age‐related neurodegenerative disease. In this
review, we carefully detail amyloid‐β metabolism and its role in AD. We also consider the …

Alzheimer s disease and oxidative stress: a review

M Pohanka - Current medicinal chemistry, 2014 - ingentaconnect.com
Alzheimer´ s disease (AD) is a neurodegenerative disorder with no known cure and rapid
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …

[HTML][HTML] Doença de Alzheimer: hipóteses etiológicas e perspectivas de tratamento

AD Falco, DS Cukierman, RA Hauser-Davis, NA Rey - Química Nova, 2016 - SciELO Brasil
With the increase in life expectancy registered in the past few decades, the prevalence of
various medical conditions related to aging has been observed, such as dementia and …

Cross-interactions between the Alzheimer disease amyloid-β peptide and other amyloid proteins: a further aspect of the amyloid cascade hypothesis

J Luo, SKTS Wärmländer, A Gräslund… - Journal of Biological …, 2016 - ASBMB
Many protein folding diseases are intimately associated with accumulation of amyloid
aggregates. The amyloid materials formed by different proteins/peptides share many …

Delineation of neuroprotective effects and possible benefits of antioxidantstherapy for the treatment of Alzheimer's diseases by targeting mitochondrial-derived …

V Walia, D Kaushik, V Mittal, K Kumar, R Verma… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

A synthetic circuit for mercury bioremediation using self-assembling functional amyloids

PKR Tay, PQ Nguyen, NS Joshi - ACS synthetic biology, 2017 - ACS Publications
Synthetic biology approaches to bioremediation are a key sustainable strategy to leverage
the self-replicating and programmable aspects of biology for environmental stewardship …