Hemorrhagic shock

JW Cannon - New England Journal of Medicine, 2018 - Mass Medical Soc
Hemorrhagic Shock | New England Journal of Medicine Skip to main content Access provided
byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine homepage …

Innate immune responses to trauma

M Huber-Lang, JD Lambris, PA Ward - Nature immunology, 2018 - nature.com
Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

[HTML][HTML] Trauma‐induced coagulopathy: the past, present, and future

LZ Kornblith, HB Moore, MJ Cohen - Journal of thrombosis and …, 2019 - Elsevier
Trauma remains a leading cause of death worldwide, and most early preventable deaths in
both the civilian and military settings are due to uncontrolled hemorrhage, despite paradigm …

Shock induced endotheliopathy (SHINE) in acute critical illness-a unifying pathophysiologic mechanism

PI Johansson, J Stensballe, SR Ostrowski - Critical Care, 2017 - Springer
One quarter of patients suffering from acute critical illness such as severe trauma, sepsis,
myocardial infarction (MI) or post cardiac arrest syndrome (PCAS) develop severe …

Immunopathophysiology of trauma-related acute kidney injury

DAC Messerer, R Halbgebauer, B Nilsson… - Nature Reviews …, 2021 - nature.com
Physical trauma can affect any individual and is globally accountable for more than one in
every ten deaths. Although direct severe kidney trauma is relatively infrequent, extrarenal …

Human glycocalyx shedding: systematic review and critical appraisal

RG Hahn, V Patel, RO Dull - Acta Anaesthesiologica …, 2021 - Wiley Online Library
Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

The role of TEG and ROTEM in damage control resuscitation

JB Brill, M Brenner, J Duchesne, D Roberts, P Ferrada… - Shock, 2021 - journals.lww.com
Trauma-induced coagulopathy is associated with very high mortality, and hemorrhage
remains the leading preventable cause of death after injury. Directed methods to combat …

Hemorrhagic blood failure: oxygen debt, coagulopathy, and endothelial damage

NJ White, KR Ward, S Pati, G Strandenes… - Journal of Trauma and …, 2017 - journals.lww.com
Trauma is responsible for 1 in 10 deaths worldwide and is the leading cause of death of
people less than 45 years old. 1 The two most common causes of death in trauma victims …

[HTML][HTML] Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma

R Halbgebauer, CK Braun, S Denk, B Mayer… - Journal of critical …, 2018 - Elsevier
Polytrauma (PT) is frequently associated with hemorrhagic shock (HS), which increases
morbidity and mortality. Although various aspects of HS have been addressed in PT …

Endotheliopathy of trauma is an on-scene phenomenon, and is associated with multiple organ dysfunction syndrome: a prospective observational study

DN Naumann, J Hazeldine, DJ Davies, J Bishop… - Shock, 2018 - journals.lww.com
Background: Trauma patients are vulnerable to coagulopathy and inflammatory dysfunction
associated with endotheliopathy of trauma (EoT). In vitro evidence has suggested that …