Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

The concept of developmental origins of health and disease (DOHaD) was initially
supported by the low birth weight and higher risk of developing cardiovascular disease in …

Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal
offspring. This constitutes a major public health concern due to increasing prevalence of …

A high-fat diet (HFD) is linked with cytokines production by non-neuronal cells within the
hypothalamus, which mediates metabolic inflammation. These cytokines then activate …

Consumption of a high-fat diet has long been known to increase risk for obesity, diabetes,
and the metabolic syndrome. Further evidence strongly suggests that these same metabolic …

This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …

The breastfeeding period is one of the most important critical windows in our development,
since milk, our first food after birth, contains several compounds, such as macronutrients …

Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally.
However, the pathogenesis remains largely unclear and the prevention and treatment are …

Obesity is a significant global health and socio-economic challenge, and considered an
important risk factor for poor health outcomes including male reproductive dysfunction and …

Environmental factors such as maternal high-fat diet (HFD) intake can increase the risk of
age-related cognitive decline in adult offspring. Epigenetic mechanisms are a possible link …