Non-steroidal anti-inflammatory drugs (NSAIDs): A current insight into its molecular mechanism eliciting organ toxicities

NK Panchal, EP Sabina - Food and Chemical Toxicology, 2023 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of medications that are routinely
been used across the world. Their analgesic, anti-inflammatory, and antipyretic effects have …

[HTML][HTML] An overview of clinical pharmacology of Ibuprofen

R Bushra, N Aslam - Oman medical journal, 2010 - ncbi.nlm.nih.gov
Ibuprofen was the first member of Propionic acid derivatives introduced in 1969. It is a
popular domestic and over the counter analgesic and antipyretic for adults and children …

Clinical pharmacokinetics of ibuprofen: the first 30 years

NM Davies - Clinical pharmacokinetics, 1998 - Springer
Ibuprofen is a chiral nonsteroidal anti-inflammatory drug (NSAID) of the 2 arylpropionic acid
(2-APA) class. A common structural feature of 2-APA NSAIDs is a sp 3-hybridised tetrahedral …

A clinical and safety review of paracetamol and ibuprofen in children

DJ Kanabar - Inflammopharmacology, 2017 - Springer
The antipyretic analgesics, paracetamol, and non-steroidal anti-inflammatory agents
NSAIDs are one of the most widely used classes of medications in children. The aim of this …

[图书][B] Principles of clinical toxicology

TA Gossel - 2018 - taylorfrancis.com
In this third edition, the editors have accounted for the numerous changes in protocols for
managing poison ingestions and have again provided an indispensable resource for all …

Over-the-counter analgesics and antipyretics: a critical assessment

EV Hersh, PA Moore, GL Ross - Clinical therapeutics, 2000 - Elsevier
BACKGROUND: It is just 100 years since the introduction of aspirin to medicine. Since then,
aspirin and its derivatives have been joined by acetaminophen, and the nonsteroidal anti …

Antimicrobial effects of antipyretics

P Zimmermann, N Curtis - Antimicrobial Agents and …, 2017 - Am Soc Microbiol
Antipyretics are some of the most commonly used drugs. Since they are often
coadministered with antimicrobial therapy, it is important to understand the interactions …

Toxic effects of nonsteroidal anti-inflammatory drugs in overdose: an overview of recent evidence on clinical effects and dose-response relationships

SC Smolinske, AH Hall, SA Vandenberg, DG Spoerke… - Drug Safety, 1990 - Springer
Nonsalicylate, nonsteroidal anti-inflammatory drugs (NSAIDs) can be divided into 4
chemical classes: acetic acids, fenamic acids, oxicams and propionic acids. Most NSAID …

The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose

LJ Hunter, DM Wood, PI Dargan - Open Access Emergency …, 2011 - Taylor & Francis
The nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, anti-
inflammatory and antipyretic actions. They are commonly taken in overdose in many areas …

Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures

A Van Esch, HA Van Steensel-Moll… - … of pediatrics & …, 1995 - jamanetwork.com
Objective: To compare the antipyretic efficacy of ibuprofen syrup (5 mg/kg per dose) and
acetaminophen syrup (10 mg/kg per dose) in children with a history of febrile seizures …