Quinazoline derivatives and hybrids: recent structures with potent bioactivity
IA Bala, AM Asiri, RM El-Shishtawy - Medicinal Chemistry Research, 2024 - Springer
Quinazolines represent a class of nitrogen-containing heterocyclics with a broad spectrum of
biological applications. Many studies have explored the medicinal qualities of quinazoline …
biological applications. Many studies have explored the medicinal qualities of quinazoline …
Design, synthesis and antitumor activity evaluation of 4, 6, 7-trisubstituted quinazoline derivatives containing benzothiazole moiety
F Yu, Y Xu, H Wang, L Chi, X Si, C Gao, H Dai… - Medicinal Chemistry …, 2023 - Springer
Abstract A series of novel 4, 6, 7-trisubstituted quinazoline derivatives containing
benzothiazole moiety were designed, synthesized and evaluated for their antitumor activity …
benzothiazole moiety were designed, synthesized and evaluated for their antitumor activity …
Proapoptotic effects of halogenated bis‐phenylthiourea derivatives in cancer cells
P Strzyga‐Łach, A Chrzanowska… - Archiv der …, 2023 - Wiley Online Library
New halogenated thiourea derivatives were synthesized via the reaction of substituted
phenylisothiocyanates with aromatic amines. Their cytotoxic activity was examined in in vitro …
phenylisothiocyanates with aromatic amines. Their cytotoxic activity was examined in in vitro …
Pharmacophore‐Based Modeling, Synthesis, and Biological Evaluation of Novel Quinazoline/Quinoline Derivatives: Discovery of EGFR Inhibitors with Low …
AE Evren, BN Sağlik Özkan… - Advanced Theory …, 2024 - Wiley Online Library
The main aim of this study is to obtain novel molecules that are more selective on cancer
cells compared to healthy cells. For this purpose, four hit molecules are identified using 11 …
cells compared to healthy cells. For this purpose, four hit molecules are identified using 11 …