Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological …

P Ferdinandy, I Andreadou, GF Baxter, HE Bøtker… - Pharmacological …, 2023 - ASPET
Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …

[HTML][HTML] Modification of ischemia/reperfusion-induced alterations in subcellular organelles by ischemic preconditioning

PS Tappia, AK Shah, B Ramjiawan… - International Journal of …, 2022 - mdpi.com
It is now well established that ischemia/reperfusion (I/R) injury is associated with the
compromised recovery of cardiac contractile function. Such an adverse effect of I/R injury in …

[HTML][HTML] Effects of ischemia-reperfusion on tubular cell membrane transporters and consequences in kidney transplantation

Q Faucher, H Alarcan, P Marquet… - Journal of Clinical …, 2020 - mdpi.com
Ischemia-reperfusion (IR)-induced acute kidney injury (IRI) is an inevitable event in kidney
transplantation. It is a complex pathophysiological process associated with numerous …

[HTML][HTML] Total saponins of Aralia elata (Miq) seem alleviate calcium homeostasis imbalance and endoplasmic reticulum stress-related apoptosis induced by …

R Wang, M Yang, M Wang, X Liu, H Xu, X Xu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Total saponins of Aralia elata (Miq) Seem (AS) from the Chinese
traditional herb Long ya Aralia chinensis L. reportedly provide cardioprotective effects, but …

The Na/K‐ATPase α1/Src interaction regulates metabolic reserve and Western diet intolerance

LC Kutz, X Cui, JX Xie, ST Mukherji… - Acta …, 2021 - Wiley Online Library
Aim Highly prevalent diseases such as insulin resistance and heart failure are characterized
by reduced metabolic flexibility and reserve. We tested whether Na/K‐ATPase (NKA) …

[HTML][HTML] Cysteine residues 244 and 458–459 within the catalytic subunit of Na, K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic …

IY Petrushanko, VA Mitkevich, VA Lakunina… - Redox biology, 2017 - Elsevier
Our previous findings suggested that reversible thiol modifications of cysteine residues
within the actuator (AD) and nucleotide binding domain (NBD) of the Na, K-ATPase may …

Isoform-specific role of Na/K-ATPase α1 in skeletal muscle

LC Kutz, ST Mukherji, X Wang… - American Journal …, 2018 - journals.physiology.org
The distribution of Na/K-ATPase α-isoforms in skeletal muscle is unique, with α1 as the
minor (15%) isoform and α2 comprising the bulk of the Na/K-ATPase pool. The acute and …

[HTML][HTML] Emerging role of non-coding RNAs and extracellular vesicles in cardioprotection by remote ischemic conditioning of the heart

M Bartekova, M Jelemensky, NS Dhalla - Reviews in Cardiovascular …, 2019 - imrpress.com
Remote ischemic conditioning of the heart (including pre-, per-, and post-conditioning) is a
phenomenon where short episodes of non-lethal ischemia in the distant vessels within the …

[HTML][HTML] Na/K-ATPase signaling and cardiac pre/postconditioning with cardiotonic steroids

PV Marck, SV Pierre - International Journal of Molecular Sciences, 2018 - mdpi.com
The first reports of cardiac Na/K-ATPase signaling, published 20 years ago, have opened
several major fields of investigations into the cardioprotective action of low/subinotropic …

Mutation analysis of the interactions between Mycobacterium tuberculosis caseinolytic protease C1 (ClpC1) and ecumicin

IP Jung, NR Ha, AR Kim, SH Kim, MY Yoon - International journal of …, 2017 - Elsevier
Ecumicin is a well-known and potent inhibitor of Mycobacterium tuberculosis. Although the
target of ecumicin is caseinolytic protease C1 (ClpC1), the exact mechanism by which …