Biogenic amine transporters for serotonin, norepinephrine and dopamine (SERT, NET and
DAT respectively), are the key players terminating transmission of these amines in the …

Since the first implant of a carbon microelectrode in a rat 35 years ago, there have been
substantial advances in the sensitivity, selectivity and temporal resolution of electrochemical …

Psychoactive β-keto amphetamines (cathinones) are sold as “bath salts” or “legal highs” and
recreationally abused. We characterized the pharmacology of a new series of cathinones …

Efflux of dopamine through the dopamine transporter (DAT) is critical for the
psychostimulatory properties of amphetamines, but the underlying mechanism is unclear …

Dopamine neurotransmission is highly dysregulated by the psychostimulant
methamphetamine, a substrate for the dopamine transporter (DAT). Through interactions …

Mood disorders cause much suffering and are the single greatest cause of lost productivity
worldwide. Although multiple medications, along with behavioral therapies, have proven …

The behavioral effects of psychomotor stimulants such as amphetamine (AMPH) arise from
their ability to elicit increases in extracellular dopamine (DA). These AMPH-induced …

The serotonin transporter (SERT) is the principal mechanism for terminating serotonin (5-
HT) signals in the nervous system and is a site of action for a variety of psychoactive drugs …

Rationale Most studies on the subjective effects of ecstasy are based on the assumption that
the substance that was taken is 3, 4-methylenedioxymethamphetamine (MDMA). However …

This chapter describes how new psychoactive substances (NPS) have been involved in fatal
intoxications from 2010 and onwards. It summarizes the circumstances, antemortem …