The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

Glucocorticoids serve as key stress response hormones that facilitate stress coping.
However, sustained glucocorticoid exposure is associated with adverse consequences on …

Neural circuits in neonatal animals contain numerous redundant synapses that are
functionally immature. During the postnatal period, unnecessary synapses are eliminated …

Abstract Innervation of Purkinje cells (PCs) by multiple climbing fibers (CFs) is refined into
mono‐innervation during the first three postnatal weeks of rodents' lives. In this review …

Elimination of early-formed redundant synapses during postnatal development is essential
for functional neural circuit formation. Purkinje cells (PCs) in the neonatal cerebellum are …

Repetitive transcranial magnetic stimulation (rTMS) is increasingly used as a treatment for
neurological and psychiatric disorders. Although the induced field is focused on a target …

Functional neural circuits in the mature animals are shaped during postnatal development
by elimination of unnecessary synapses and strengthening of necessary ones among …

Although the organization of neuronal circuitry is shaped by activity patterns, the capacity to
modify and/or optimize the structure and function of whole projection pathways using …

Evidences from studies on patients with overt cerebellar diseases as well as on healthy
individuals suggest a possible role for the cerebellum in cognition, mood and behaviour …

Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by an
abnormal expansion of CAG repeats in the Ataxin-1 (ATXN1) gene and characterized by …