I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) characterized by a type 2
immune signature often have severe and recurrent disease. Lower airway conditions such …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Background Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by
mucosal inflammation in the nose and paranasal sinuses. Inflammation in CRS is also …

Objective This update of a 2007 guideline from the American Academy of Otolaryngology—
Head and Neck Surgery Foundation provides evidence-based recommendations to manage …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

Background Type 2 inflammation is common in numerous atopic/allergic diseases and can
be identified by elevated biomarker levels. Dupilumab, a fully human monoclonal antibody …

Background The objective of this study was to describe the first US‐based study to use the
European Position Paper on Rhinosinusitis (EPOS) criteria to study the prevalence of …

Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …