Non-eosinophilic asthma: current perspectives

I Esteban-Gorgojo, D Antolín-Amérigo… - Journal of asthma …, 2018 - Taylor & Francis
Although non-eosinophilic asthma (NEA) is not the best known and most prevalent asthma
phenotype, its importance cannot be underestimated. NEA is characterized by airway …

Obesity and the lung: what we know today

JM Brock, A Billeter, BP Müller-Stich, F Herth - Respiration, 2021 - karger.com
Obesity is becoming more and more prevalent especially in Western industrial nations. The
understanding of adipose tissue as an endocrine organ as well as the detection of …

Association between overweight or obesity and the risk for childhood asthma and wheeze: An updated meta‐analysis on 18 articles and 73 252 children

X Deng, J Ma, Y Yuan, Z Zhang, W Niu - Pediatric obesity, 2019 - Wiley Online Library
Background Overweight or obesity is increasingly recognized as a possible risk factor for
childhood asthma. Objectives We aimed to meta‐analyse the association between …

[HTML][HTML] Role of leptin as a link between asthma and obesity: a systematic review and meta-analysis

H Sánchez-Ortega, C Jiménez-Cortegana… - International Journal of …, 2022 - mdpi.com
Asthma and obesity are considered as highly prevalent diseases with a great impact on
public health. Obesity has been demonstrated to be an aggravating factor in the …

Cold temperature and sudden temperature drop as novel risk factors of asthma exacerbation: a longitudinal study in 18 Chinese cities

Y Zhu, T Yang, S Huang, H Li, J Lei, X Xue… - Science of The Total …, 2022 - Elsevier
Background Few studies have explored the role of ambient temperature in asthma
exacerbation. Objective We aimed to explore the association of temperature with diurnal …

[HTML][HTML] Adiponectin and asthma: Knowns, unknowns and controversies

MR Otelea, OC Arghir, C Zugravu, A Rascu - International Journal of …, 2021 - mdpi.com
Adiponectin is an adipokine associated with the healthy obese phenotype. Adiponectin
increases insulin sensitivity and has cardio and vascular protection actions. Studies related …

Leptin favors Th17/Treg cell subsets imbalance associated with allergic asthma severity

CM Vollmer, ASO Dias, LM Lopes… - Clinical and …, 2022 - Wiley Online Library
Background Obesity has often been associated with severe allergic asthma (AA). Here, we
analyzed the frequency of different circulating CD4+ T‐cell subsets from lean, overweight …

Effect of obesity on airway and systemic inflammation in adults with asthma: a systematic review and meta-analysis

HA Scott, SHM Ng, RF McLoughlin, SR Valkenborghs… - Thorax, 2023 - thorax.bmj.com
Background Obesity is associated with more severe asthma, however, the mechanisms
responsible are poorly understood. Obesity is also associated with low-grade systemic …

[HTML][HTML] Regulation of lung inflammation by adiponectin

JY Lim, SP Templeton - Frontiers in Immunology, 2023 - frontiersin.org
Adiponectin is an insulin sensitizing hormone that also plays a role in the regulation of
inflammation. Although adiponectin can exert pro-inflammatory effects, more studies have …

Lipid mediators and asthma: Scope of therapeutics

N Monga, GS Sethi, KK Kondepudi, AS Naura - Biochemical Pharmacology, 2020 - Elsevier
Lipids and their mediators are known to play a pro-inflammatory role in several human
diseases including asthma. The influence of leukotrienes and prostaglandins through …