Exploring foods as natural sources of FAHFAs—A review of occurrence, extraction, analytical techniques and emerging bioactive potential

TM Olajide, W Cao - Trends in Food Science & Technology, 2022 - Elsevier
Background Fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of recently
discovered novel lipids gaining increasing attention due to their diverse biological roles …

The chemical and biological characteristics of fatty acid esters of hydroxyl fatty acids

S Zhu, Y He, JN Lei, YF Liu, YJ Xu - Nutrition Reviews, 2024 - academic.oup.com
With the continuous advancements in detection methods and the exploration of unknown
substances, an increasing number of bioactive compounds are being discovered. Fatty acid …

The role of peroxiredoxin 6 in biosynthesis of FAHFAs

V Paluchova, T Cajka, T Durand, C Vigor… - Free Radical Biology …, 2022 - Elsevier
Abstract Peroxiredoxin 6 (Prdx6) is a multifunctional enzyme, a unique member of the
peroxiredoxin family, with an important role in antioxidant defense. Moreover, it has also …

Comprehensive lipidomic profiling of human milk from lactating women across varying lactation stages and gestational ages

M Zhao, Z Chen, D Ye, R Yu, Q Yang - Food chemistry, 2025 - Elsevier
An untargeted lipidomic analysis was conducted to investigate the lipid composition of
human milk across different lactation stages and gestational ages systematically. A total of …

[HTML][HTML] Analysis of fatty acid esters of hydroxy fatty acids in edible mushrooms

F Martínez-Ramírez, M Riecan, T Cajka, O Kuda - LWT, 2023 - Elsevier
Edible mushrooms are consumed worldwide. The overall amount of lipids in mushrooms is
small and consists of complex lipids, such as triacylglycerols, phospholipids, and sterols …

[HTML][HTML] The production of FAHFA is enhanced when Haematococcus pluvialis is grown in CO2

M Casula, G Fais, C Manis, P Scano, A Concas, G Cao… - Food Chemistry, 2024 - Elsevier
Microalgae are considered as a potential source of bioactive compounds to be used in
different fields including food and pharmaceutical industry. In this context, fatty acid esters of …

[HTML][HTML] Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids

M Riecan, V Domanska, C Lupu, M Patel… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous bioactive lipids known for
their anti-inflammatory and anti-diabetic properties. Despite their therapeutic potential, little …

Characterization of triacylglycerol estolide isomers using high-resolution tandem mass spectrometry with nanoelectrospray Ionization

L Cudlman, A Machara, V Vrkoslav, M Polášek… - Biomolecules, 2023 - mdpi.com
Triacylglycerol estolides (TG-EST) are biologically active lipids extensively studied for their
anti-inflammatory and anti-diabetic properties. In this work, eight standards of TG-EST were …

[HTML][HTML] Tissue-specific sex difference in the metabolism of fatty acid esters of hydroxy fatty acids

M Riecan, V Domanska, C Lupu, M Patel… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous bioactive lipids known for
their anti-inflammatory and anti-diabetic properties. Despite their therapeutic potential, little …

Role of antioxidant defense in the synthesis of antidiabetic lipokines

V Domanská - 2023 - dspace.cuni.cz
Fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered group of lipokines
consisting of a fatty acid attached to a hydroxy fatty acid with an ester bond resulting in a …