[HTML][HTML] 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American …

DO Kleindorfer, A Towfighi, S Chaturvedi, KM Cockroft… - Stroke, 2021 - journals.lww.com
1. Specific recommendations for prevention strategies often depend on the ischemic
stroke/transient ischemic attack subtype. Therefore, new in this guideline is a section …

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

JS Smolen, R Landewé, J Bijlsma… - Annals of the …, 2017 - ard.bmj.com
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international …

Network-based approach to prediction and population-based validation of in silico drug repurposing

F Cheng, RJ Desai, DE Handy, R Wang… - Nature …, 2018 - nature.com
Here we identify hundreds of new drug-disease associations for over 900 FDA-approved
drugs by quantifying the network proximity of disease genes and drug targets in the human …

Cardiac complications attributed to chloroquine and hydroxychloroquine: a systematic review of the literature

C Chatre, F Roubille, H Vernhet, C Jorgensen, YM Pers - Drug safety, 2018 - Springer
Introduction Chloroquine and hydroxychloroquine are widely used in the long-term
treatment of connective tissue disease and usually considered safe. However, chloroquine …

Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

BR England, GM Thiele, DR Anderson, TR Mikuls - Bmj, 2018 - bmj.com
Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

Rheumatoid arthritis: recent advances on its etiology, role of cytokines and pharmacotherapy

J Alam, I Jantan, SNA Bukhari - Biomedicine & pharmacotherapy, 2017 - Elsevier
An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …

The therapeutic landscape of rheumatoid arthritis: current state and future directions

S Shams, JM Martinez, JRD Dawson, J Flores… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …

Metabolic and cardiovascular benefits of hydroxychloroquine in patients with rheumatoid arthritis: a systematic review and meta-analysis

C Rempenault, B Combe, T Barnetche… - Annals of the …, 2018 - ard.bmj.com
Objective Cardiovascular disease (CVD) is the leading cause of mortality in patients with
rheumatoid arthritis (RA). Hydroxychloroquine (HCQ) has been shown to improve survival …

Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review

TX Zhao, Z Mallat - Journal of the American College of Cardiology, 2019 - jacc.org
Atherosclerosis has long been known as an inflammatory disease. However, whether
targeting inflammation improves outcomes was unproven until the recent results of CANTOS …