Clinical management and therapeutic strategies for the thyroid-associated ophthalmopathy: current and future perspectives

S Mishra, VK Maurya, S Kumar, Ankita, A Kaur… - Current eye …, 2020 - Taylor & Francis
Purpose TAO is an organ specific autoimmune disease associated with thyroid, and
inflammation of the orbit and periorbital tissues, which is different from systemic autoimmune …

New therapeutic horizon of Graves' hyperthyroidism: treatment regimens based on immunology and ingredients from traditional Chinese medicine

Q He, H Dong, M Gong, Y Guo, Q Xia… - Frontiers in …, 2022 - frontiersin.org
Graves' disease is an autoimmune disease characterized by goiter and hyperthyroidism,
and 25% patients develop GO. Traditional treatment options, such as antithyroid drugs …

Orphan nuclear receptors in angiogenesis and follicular development

A Guzmán, CHK Hughes, BD Murphy - Reproduction, 2021 - rep.bioscientifica.com
Orphan nuclear receptors (ONRs) are a subset of the nuclear receptor family that lacks
known endogenous ligands. Among 48 nuclear receptors identified in humans, 25 are …

Update on the clinical assessment and management of thyroid eye disease

JCP Roos, R Murthy - Current Opinion in Ophthalmology, 2019 - journals.lww.com
Thyroid eye disease research is enjoying a renaissance with advances in both monitoring
and treatment coupled with a renewed emphasis on a holisitic approach, which includes …

Mechanisms of Spica Prunellae against thyroid-associated Ophthalmopathy based on network pharmacology and molecular docking

Y Zhang, X Li, C Guo, J Dong, L Liao - BMC Complementary Medicine and …, 2020 - Springer
Background Thyroid-associated ophthalmopathy (TAO) is an autoimmune inflammatory
disorder, which lacks effective treatment currently. Spica Prunellae (SP) is popularly used for …

Inhibition of fibrotic contraction by sirolimus (rapamycin) in an ex vivo model of thyroid eye disease

JCP Roos, V Eglitis, R Murthy - Ophthalmic Plastic & …, 2021 - journals.lww.com
Background: Thyroid eye disease (TED) is characterized by orbital inflammation and
complicated by extraocular muscle fibrosis. Treatment with rapamycin/sirolimus has been …

Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism

L Peng, R Yang, Z Wang, H Jian, X Tan, J Li, Z He… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Cisplatin resistance often leads to treatment futility and elevated mortality
rates in patients with lung cancer. One promising strategy to address this challenge involves …

Identification of tRNA-Related Fragments and Their Potential Regulatory Effects in Thyroid-Associated Ophthalmopathy

Z Yue, F Tong, C Zeng, R Wei - Frontiers in Genetics, 2022 - frontiersin.org
Recently, the potential role of tRNA-related fragments (tRFs) in ophthalmic diseases has
been extensively researched. However, systematic studies on the potential regulatory effects …

Comprehensive Analysis of lncRNA Expression Profile and the Potential Role of ENST00000604491 in Graves' Disease

Y Liu, J Zou, J Xu, X Wang, J Xing… - Journal of …, 2022 - Wiley Online Library
Background. Graves' disease (GD) is one of the most common autoimmune diseases
worldwide and develops in 20 to 50 cases per 100,000 persons annually. Long noncoding …

[HTML][HTML] ADIPONECTIN LEVELS IN GRAVES'DISEASE–SYSTEMATIC REVIEW AND META-ANALYSIS

A Ismaiel, AL Abunahleh, A Elsayed… - Acta Endocrinologica …, 2023 - ncbi.nlm.nih.gov
Objective Although the association between adiponectin and Graves' disease has been
studied, the existing data is inconsistent. Therefore, we conducted this systematic review …