Oxytocin modulates proliferation and stress responses of human skin cells: implications for atopic dermatitis

V Deing, D Roggenkamp, J Kühnl… - Experimental …, 2013 - Wiley Online Library
The neuropeptide hormone oxytocin (OXT) mediates a wide spectrum of tissue‐specific
actions, ranging from cell growth, cell differentiation, sodium excretion to stress responses …

Neuropeptides in sepsis: from brain pathology to systemic inflammation

FP da Silva, MCC Machado, IT Velasco - Peptides, 2013 - Elsevier
Septic encephalopathy is frequently diagnosed in critically ill patients and in up to 70% of
patients with severe systemic infection [19]. The syndrome is defined by diffuse cerebral …

Oxytocin affects nitric oxide and cytokine production by sepsis-sensitized macrophages

GR Oliveira-Pelegrin, RS Saia, EC Cárnio… - …, 2013 - karger.com
Background/Aim: Oxytocin (OXT) secretion during cecal ligation puncture (CLP)-induced
sepsis has not yet been examined. Although immune properties have been attributed to …

Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis

LS Silva, CHR Catalão, TT Felippotti… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Curcumin has been reported to have anti-inflammatory, antioxidant and
hypoglycaemic properties, besides reducing mortality in sepsis. Objective: This study …

Recent advances in the understanding of sepsis-induced alterations in the neuroendocrine system

F Wahab, B Atika… - … Metabolic & Immune …, 2013 - ingentaconnect.com
Sepsis is a fatal systemic inflammatory disease. It is caused by an immune system
inflammatory response to the entry of microorganisms or their products into the blood …

Interleukin-1 receptor antagonist decreases hypothalamic oxidative stress during experimental sepsis

F Wahab, NN Santos-Junior… - Molecular …, 2016 - Springer
In our previous work, we demonstrated that the intracerebroventricular (icv) injection of an
interleukin-1 receptor antagonist (IL-1ra) prevented the impairment in vasopressin secretion …

Impairment of osmotic challenge-induced neurohypophyseal hormones secretion in sepsis survivor rats

NN Santos-Junior, LHA Costa, CHR Catalão… - Pituitary, 2017 - Springer
Abstract Background/Purpose Recent studies have reported that sepsis survivors show
impaired central nervous system functions. The osmoregulation in this post-sepsis condition …

Cellular bioenergetics changes in magnocellular neurons may affect copeptin expression in the late phase of sepsis

GR Oliveira-Pelegrin, PJ Basso, MJA Rocha - Journal of neuroimmunology, 2014 - Elsevier
We investigated whether inflammatory mediators during cecal ligation and puncture (CLP)-
induced sepsis may diminish copeptin expression in magnocellular neurons, thus affecting …

Interleukin-1 receptor antagonist decreases cerebrospinal fluid nitric oxide levels and increases vasopressin secretion in the late phase of sepsis in rats

F Wahab, LF Tazinafo, EC Cárnio, FA Aguila… - Endocrine, 2015 - Springer
The aim of this study was to analyze the effect of IL-1ra (an Interleukin-1 receptor antagonist)
on sepsis-induced alterations in vasopressin (AVP) and nitric oxide (NO) levels. In addition …

[HTML][HTML] Cleaved caspase-3 expression in hypothalamic magnocellular neurons may affect vasopressin secretion during experimental polymicrobial sepsis

GR Oliveira-Pelegrin, PJ Basso, AS Soares… - Journal of …, 2013 - Elsevier
We investigated whether the vasopressin (AVP) secretion deficiency observed during cecal
ligation and puncture (CLP)-induced sepsis may be caused by apoptosis in hypothalamic …