[HTML][HTML] Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …
Emerging building blocks for medicinal chemistry: recent synthetic advances
OO Grygorenko, DM Volochnyuk… - European Journal of …, 2021 - Wiley Online Library
Current medicinal chemistry relies heavily on the quality of building blocks, ie reagents used
to introduce chemical diversity into the target molecules. The last decade witnessed an …
to introduce chemical diversity into the target molecules. The last decade witnessed an …
Radical Hydro‐Fluorosulfonylation of Unactivated Alkenes and Alkynes
P Wang, H Zhang, M Zhao, S Ji, L Lin… - Angewandte Chemie …, 2022 - Wiley Online Library
Recently, radical fluorosulfonylation is emerging as an appealing approach for the synthesis
of sulfonyl fluorides, which are highly in demand in various disciplines, particularly in …
of sulfonyl fluorides, which are highly in demand in various disciplines, particularly in …
Electrochemical Oxo‐Fluorosulfonylation of Alkynes under Air: Facile Access to β‐Keto Sulfonyl Fluorides
D Chen, X Nie, Q Feng, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Radical fluorosulfonylation is emerging as an appealing approach for the synthesis of
sulfonyl fluorides, which have widespread applications in many fields, in particular in the …
sulfonyl fluorides, which have widespread applications in many fields, in particular in the …
[HTML][HTML] An overview of 1, 2, 3-triazole-containing hybrids and their potential anticholinesterase activities
Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …
Introducing A New Class of Sulfonyl Fluoride Hubs via Radical Chloro‐Fluorosulfonylation of Alkynes
X Nie, T Xu, Y Hong, H Zhang, C Mao… - Angewandte Chemie …, 2021 - Wiley Online Library
Sulfonyl fluorides have widespread applications in many important fields, including ligation
chemistry, chemical biology, and drug discovery. Therefore, new methods to increase the …
chemistry, chemical biology, and drug discovery. Therefore, new methods to increase the …
Radical fluorosulfonylation: accessing alkenyl sulfonyl fluorides from alkenes
X Nie, T Xu, J Song, A Devaraj, B Zhang… - Angewandte …, 2021 - Wiley Online Library
Sulfonyl fluorides have widespread applications in many fields. In particular, their unique
biological activity has drawn considerable research interest in the context of chemical …
biological activity has drawn considerable research interest in the context of chemical …
Linkage chemistry of S (VI) fluorides
D Zeng, WP Deng, X Jiang - Chemistry–A European Journal, 2023 - Wiley Online Library
Sulfur (VI)‐fluoride exchange linkage as a next generation of click chemistry was introduced
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …
Phosphorus fluoride exchange: Multidimensional catalytic click chemistry from phosphorus connective hubs
S Sun, JA Homer, CJ Smedley, QQ Cheng… - Chem, 2023 - cell.com
Phosphorus fluoride exchange (PFEx) represents a cutting-edge advancement in catalytic
click-reaction technology. Drawing inspiration from nature's phosphate connectors, PFEx …
click-reaction technology. Drawing inspiration from nature's phosphate connectors, PFEx …
Radical Fluorosulfonyl Heteroarylation of Unactivated Alkenes with Quinoxalin-2(1H)-ones and Related N-Heterocycles
The incorporation of sulfonyl fluoride groups into molecules has been proved effective to
enhance their biological activities or introduce new functions. Herein, we report a transition …
enhance their biological activities or introduce new functions. Herein, we report a transition …