Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

Cholangiocarcinoma (CCA) is a malignant tumour arising from the biliary system. In Europe,
this tumour frequently presents as a sporadic cancer in patients without defined risk factors …

The high mortality rate of cholangiocarcinoma (CCA) is due, in part, to the lack of non‐
invasive approaches able to accurately detect this silent tumour at early stages, when …

Cholangiocarcinoma (CCA) is an aggressive tumor with a poor prognosis due to its late
clinical presentation and the lack of effective non-surgical therapies. Unfortunately, most of …

In recent years, the incidence of both liver and biliary tract cancer has increased.
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are the two most common …

SOX9 has been previously shown to be involved in hepatocellular carcinoma (HCC) and
other types of cancer. However, prognostic studies so far involved rather small cohorts or …

Liver regeneration after most forms of injury is mediated through the proliferation of
hepatocytes. However, when hepatocyte proliferation is impaired, such as during chronic …

Background Sex-determining region Y-box (SRY-box) containing gene 9 (SOX9) expression
confers cancer stem cell features. However, SOX9 function in intrahepatic …

In addition to its well-established role in embryo development, epithelial-to-mesenchymal
transition (EMT) has been proposed as a general mechanism favoring tumor metastatization …

Cholangiocarcinoma (CCA) comprises of extra-hepatic cholangiocarcinoma and
intrahepatic cholangiocarcinoma cancers as a result of inflammation of epithelium cell lining …