The bacterial membrane provides a target for antimicrobial peptides. There are two groups
of bacteria that have characteristically different surface membranes. One is the Gram …

Persistent infections involving slow-growing or non-growing bacteria are hard to treat with
antibiotics that target biosynthetic processes in growing cells. Consequently, there is a need …

Mycobacterium tuberculosis (Mtb) lipids are indelibly imprinted in just about every key
aspect of tuberculosis (TB) basic and translational research. Although the interest in these …

Mycobacterial persisters, the survivors from antibiotic exposure, necessitate the lengthy
treatment of tuberculosis (TB) and pose a significant challenge for our control of the disease …

The aim of this review is to present the current state of knowledge on human latent
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …

We report the discovery of a series of new drug leads that have potent activity against
Mycobacterium tuberculosis as well as against other bacteria, fungi, and a malaria parasite …

ABSTRACT MmpL3, a resistance-nodulation-division (RND) superfamily transporter, has
been implicated in the formation of the outer membrane of Mycobacterium tuberculosis; …

Mycobacterium tuberculosis remains a health concern due to its ability to enter a non-
replicative dormant state linked to drug resistance. Understanding transitions into and out of …

The genus Mycobacterium comprises a group of obligately aerobic bacteria that have
adapted to inhabit a wide range of intracellular and extracellular environments. A …

Antibacterial agents have saved many lives and helped the growth of modern medicine over
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …