[HTML][HTML] Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review
L Schiffer, L Barnard, ES Baranowski… - The Journal of steroid …, 2019 - Elsevier
Advances in technology have allowed for the sensitive, specific, and simultaneous
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …
Androgen signaling in prostate cancer
The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer.
Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has …
Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has …
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders
WL Miller, RJ Auchus - Endocrine reviews, 2011 - academic.oup.com
Steroidogenesis, the processes by which cholesterol is converted to steroid hormones,
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …
11-Oxygenated androgens in health and disease
The adrenal gland is a source of sex steroid precursors, and its activity is particularly
relevant during fetal development and adrenarche. Following puberty, the synthesis of …
relevant during fetal development and adrenarche. Following puberty, the synthesis of …
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
AH Payne, DB Hales - Endocrine reviews, 2004 - academic.oup.com
Significant advances have taken place in our knowledge of the enzymes involved in steroid
hormone biosynthesis since the last comprehensive review in 1988. Major developments …
hormone biosynthesis since the last comprehensive review in 1988. Major developments …
Functional role of estrogen metabolism in target cells: review and perspectives.
BT Zhu, AH Conney - Carcinogenesis, 1998 - academic.oup.com
Cytochrome P450 enzymes that metabolize estrogens are expressed in the mammary
gland, uterus, brain and other target tissues for estrogen action, and this results in the …
gland, uterus, brain and other target tissues for estrogen action, and this results in the …
[HTML][HTML] Is dehydroepiandrosterone a hormone?
Dehydroepiandrosterone (DHEA) is not a hormone but it is a very important prohormone
secreted in large amounts by the adrenals in humans and other primates, but not in lower …
secreted in large amounts by the adrenals in humans and other primates, but not in lower …
Sex steroids and bone
JE Compston - Physiological reviews, 2001 - journals.physiology.org
Sex steroids are essential for skeletal development and the maintenance of bone health
throughout adult life, and estrogen deficiency at menopause is a major pathogenetic factor …
throughout adult life, and estrogen deficiency at menopause is a major pathogenetic factor …
[HTML][HTML] Recent advances on endocrine disrupting effects of UV filters
J Wang, L Pan, S Wu, L Lu, Y Xu, Y Zhu, M Guo… - International journal of …, 2016 - mdpi.com
Ultraviolet (UV) filters are used widely in cosmetics, plastics, adhesives and other industrial
products to protect human skin or products against direct exposure to deleterious UV …
products to protect human skin or products against direct exposure to deleterious UV …
Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism
KH Storbeck, L Schiffer, ES Baranowski… - Endocrine …, 2019 - academic.oup.com
Steroid biosynthesis and metabolism are reflected by the serum steroid metabolome and, in
even more detail, by the 24-hour urine steroid metabolome, which can provide unique …
even more detail, by the 24-hour urine steroid metabolome, which can provide unique …