Emerging Trends in Cross-Coupling: Twelve-Electron-Based L1Pd(0) Catalysts, Their Mechanism of Action, and Selected Applications
SJ Firsan, V Sivakumar, TJ Colacot - Chemical Reviews, 2022 - ACS Publications
Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …
species in the cross-coupling cycle. Today, there are methods available to generate the …
Contemporary synthetic strategies in organofluorine chemistry
R Britton, V Gouverneur, JH Lin, M Meanwell… - Nature Reviews …, 2021 - nature.com
Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …
Transformations of less-activated phenols and phenol derivatives via C–O cleavage
Employing phenols and phenol derivatives as electrophiles for cross-coupling reactions has
numerous advantages over commonly used aryl halides in terms of environmental …
numerous advantages over commonly used aryl halides in terms of environmental …
Next generation of fluorine-containing pharmaceuticals, compounds currently in phase II–III clinical trials of major pharmaceutical companies: new structural trends …
Y Zhou, J Wang, Z Gu, S Wang, W Zhu… - Chemical …, 2016 - ACS Publications
Fluoroorganic chemistry has become essential in the evolution of many different but
interconnected research fields. These include the development of new materials with a …
interconnected research fields. These include the development of new materials with a …
The fluorination of C− H bonds: developments and perspectives
R Szpera, DFJ Moseley, LB Smith… - Angewandte Chemie …, 2019 - Wiley Online Library
This Review summarizes advances in fluorination by C (sp2)− H and C (sp3)− H activation.
Transition‐metal‐catalyzed approaches championed by palladium have allowed the …
Transition‐metal‐catalyzed approaches championed by palladium have allowed the …
Applications of fluorine in medicinal chemistry
EP Gillis, KJ Eastman, MD Hill… - Journal of medicinal …, 2015 - ACS Publications
The role of fluorine in drug design and development is expanding rapidly as we learn more
about the unique properties associated with this unusual element and how to deploy it with …
about the unique properties associated with this unusual element and how to deploy it with …
Photoredox catalysis with aryl sulfonium salts enables site-selective late-stage fluorination
Photoredox catalysis, especially in combination with transition metal catalysis, can produce
redox states of transition metal catalysts to facilitate challenging bond formations that are not …
redox states of transition metal catalysts to facilitate challenging bond formations that are not …
18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography
S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …
imaging techniques such as positron emission tomography (PET). As such, PET can track …
Modern transition-metal-catalyzed carbon–halogen bond formation
The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …
number of transformations which install the carbon–halogen motif. Traditional routes to …
Monofluorination of organic compounds: 10 years of innovation
PA Champagne, J Desroches, JD Hamel… - Chemical …, 2015 - ACS Publications
Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …
to the monofluorination of organic compounds, ie, synthetic methods allowing the …