Clinical applications of naturally derived biopolymer-based scaffolds for regenerative medicine

WL Stoppel, CE Ghezzi, SL McNamara, LDB Iii… - Annals of biomedical …, 2015 - Springer
Naturally derived polymeric biomaterials, such as collagens, silks, elastins, alginates, and
fibrins are utilized in tissue engineering due to their biocompatibility, bioactivity, and tunable …

Health benefits of manuka honey as an essential constituent for tissue regeneration

K Niaz, F Maqbool, H Bahadar… - Current drug …, 2017 - ingentaconnect.com
Background: Honey is known for its therapeutic properties from ancient civilizations.
Recently, the mechanism of action of Manuka honey in wound healing, epithelial …

Next generation human brain models: engineered flat brain organoids featuring gyrification

TSP Rothenbücher, H Gürbüz, MP Pereira… - …, 2021 - iopscience.iop.org
Brain organoids are considered to be a highly promising in vitro model for the study of the
human brain and, despite their various shortcomings, have already been used widely in …

Influence of internal pore architecture on biological and mechanical properties of three‐dimensional fiber deposited scaffolds for bone regeneration

B Ostrowska, A Di Luca, L Moroni… - Journal of biomedical …, 2016 - Wiley Online Library
Fused deposition modeling has been used to fabricate three‐dimensional (3D) scaffolds for
tissue engineering applications, because it allows to tailor their pore network. Despite the …

Superior calvarial bone regeneration using pentenoate-functionalized hyaluronic acid hydrogels with devitalized tendon particles

JM Townsend, BT Andrews, Y Feng, J Wang, RJ Nudo… - Acta biomaterialia, 2018 - Elsevier
Traumatic brain injury (TBI) is a life-threatening condition defined by internal brain
herniation. Severe TBI is commonly treated by a two-stage surgical intervention, where …

Clinical outcomes of 3D-printed bioresorbable scaffolds for bone tissue engineering—A pilot study on 126 patients for burrhole covers in subdural hematoma

EMS Toh, AA Thenpandiyan, ASC Foo, JJY Zhang… - Biomedicines, 2022 - mdpi.com
Burrhole craniostomy is commonly performed for subdural hematoma (SDH) evacuation, but
residual scalp depressions are often cosmetically suboptimal for patients. OsteoplugTM, a …

Thiolated bone and tendon tissue particles covalently bound in hydrogels for in vivo calvarial bone regeneration

JM Townsend, G Sali, HB Homburg, NT Cassidy… - Acta biomaterialia, 2020 - Elsevier
Bone regeneration of large cranial defects, potentially including traumatic brain injury (TBI)
treatment, presents a major problem with non-crosslinking, clinically available products due …

Bioactivity and bone cell formation with poly-ε-caprolactone/bioceramic 3D porous scaffolds

PK Juan, FY Fan, WC Lin, PB Liao, CF Huang… - Polymers, 2021 - mdpi.com
This study applied poly-ε-caprolactone (PCL), a biomedical ceramic powder as an additive
(nano-hydroxyapatite (nHA) or β-tricalcium diphosphate (β-TCP)), and sodium chloride …

Combined bioscaffold with stem cells and exosomes can improve traumatic brain injury

J Yuan, BOA Botchway, Y Zhang, X Wang… - Stem Cell Reviews and …, 2020 - Springer
The intricacy of the brain, along with the existence of blood brain barrier (BBB) does
complicate the delivery of effective therapeutics through simple intravascular injection …

Biomimetic honeycomb-patterned surface as the tunable cell adhesion scaffold

S Chen, X Lu, Y Hu, Q Lu - Biomaterials science, 2015 - pubs.rsc.org
Inspired by the typically adhesive behaviors of fish skin and Parthenocissus tricuspidata, two
different decorations of polystyrene honeycomb membrane (PSHCM) prepared by the …