The plasma membrane in eukaryotic cells contains microdomains that are enriched in
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …

Signal transduction is initiated by complex protein–protein interactions between ligands,
receptors and kinases, to name only a few. It is now becoming clear that lipid micro …

▪ Abstract Recent studies showing that detergent-resistant membrane fragments can be
isolated from cells suggest that biological membranes are not always in a liquid-crystalline …

Lipid rafts are subdomains of the plasma membrane that contain high concentrations of
cholesterol and glycosphingolipids. They exist as distinct liquid-ordered regions of the …

The cell biology of caveolae is a rapidly growing area of biomedical research. Caveolae are
known primarily for their ability to transport molecules across endothelial cells, but modern …

Background: Coagulopathy is present at admission in 25% of trauma patients, is associated
with shock and a 5-fold increase in mortality. The coagulopathy has recently been …

Caveolae are flask‐shaped invaginations present in the plasma membrane of many cell
types. They have long been implicated in endocytosis, transcytosis, and cell signaling …

This review addresses classical questions concerning microvascular permeabiltiy in the light
of recent experimental work on intact microvascular beds, single perfused microvessels, and …

Investigators have been studying the expression and activity of proteases in the final steps of
tumor progression, invasion and metastasis, for the past 30 years. Recent studies, however …

Lipid rafts are membrane microdomains that are enriched in cholesterol and
glycosphingolipids. They have been implicated in processes as diverse as signal …