Cell surface remodeling by plasmin: a new function for an old enzyme
EI Deryugina, JP Quigley - BioMed Research International, 2012 - Wiley Online Library
Plasmin, one of the most potent and reactive serine proteases, is involved in various
physiological processes, including embryo development, thrombolysis, wound healing and …
physiological processes, including embryo development, thrombolysis, wound healing and …
Emerging photodynamic/sonodynamic therapies for urological cancers: progress and challenges
X Hu, YS Zhang, YC Liu, N Wang, XT Zeng… - Journal of …, 2022 - Springer
Photodynamic therapy (PDT), and sonodynamic therapy (SDT) that developed from PDT,
have been studied for decades to treat solid tumors. Compared with other deep tumors, the …
have been studied for decades to treat solid tumors. Compared with other deep tumors, the …
Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression
J Hao, H Chen, MC Madigan, PJ Cozzi… - British journal of …, 2010 - nature.com
Background: The aim of this study is to seek an association between markers of metastatic
potential, drug resistance-related protein and monocarboxylate transporters in prostate …
potential, drug resistance-related protein and monocarboxylate transporters in prostate …
Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target
KC Hsiao, NY Shih, HL Fang, TS Huang, CC Kuo… - PloS one, 2013 - journals.plos.org
In previous research, we found α-enolase to be inversely correlated with progression-free
and overall survival in lung cancer patients and detected α-enolase on the surface of lung …
and overall survival in lung cancer patients and detected α-enolase on the surface of lung …
[HTML][HTML] Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer
JT Zhang, XH Jiang, C Xie, H Cheng, J Da Dong… - … et Biophysica Acta (BBA …, 2013 - Elsevier
The epithelial-to-mesenchymal transition (EMT), a process involving the breakdown of cell–
cell junctions and loss of epithelial polarity, is closely related to cancer development and …
cell junctions and loss of epithelial polarity, is closely related to cancer development and …
Prostate cancer relevant antigens and enzymes for targeted drug delivery
Chemotherapy is one of the most widely used approaches in combating advanced prostate
cancer, but its therapeutic efficacy is usually insufficient due to poor specificity and …
cancer, but its therapeutic efficacy is usually insufficient due to poor specificity and …
CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer
C Xie, XH Jiang, JT Zhang, TT Sun, JD Dong… - Oncogene, 2013 - nature.com
Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is expressed in the
epithelial cells of a wide range of organs/tissues from which most cancers are derived …
epithelial cells of a wide range of organs/tissues from which most cancers are derived …
Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy
AP Mazar - Clinical cancer research, 2008 - AACR
The urokinase plasminogen activator receptor (uPAR) has been implicated in the growth,
metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is part …
metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is part …
An anti-urokinase plasminogen activator receptor antibody (ATN-658) blocks prostate cancer invasion, migration, growth, and experimental skeletal metastasis in vitro …
SA Rabbani, B Ateeq, A Arakelian, ML Valentino… - Neoplasia, 2010 - Elsevier
Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays
important roles in the growth, invasion, and metastasis of a number of cancers. In the …
important roles in the growth, invasion, and metastasis of a number of cancers. In the …
Targeting uPA/uPAR in prostate cancer
Y Li, PJ Cozzi - Cancer Treatment Reviews, 2007 - Elsevier
Prostate cancer (CaP) is one of the most common malignancies in men, with an increasing
incidence. Despite significant advances in surgery, chemotherapy and radiotherapy to treat …
incidence. Despite significant advances in surgery, chemotherapy and radiotherapy to treat …