Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are
prevalent conditions with deleterious consequences on the health and quality of life. Age …

A harmonized interplay between the central nervous system and the five peripheral end
organs is how the vestibular system helps organisms feel a sense of balance and motion in …

Tmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction
channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner …

Given the interdependence of multiple factors in age-related vestibular loss (eg, balance,
vision, cognition), it is important to examine the individual contributions of these factors with …

Introduction Occupational workers are increasingly aware of the risk of noise overexposure
to the auditory system but lack awareness about potential risks to the vestibular system. The …

While age-related auditory deficits and cochlear alterations are well described, those
affecting the vestibular sensory organs and more broadly the central vestibular pathways are …

Age-related loss of vestibular function and hearing are common disorders that arise from the
loss of function of the inner ear and significantly decrease quality of life. The underlying …

In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the
vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic …

The different clinical entities grouped under the term peripheral vestibulopathies (PVs) or
peripheral vestibular disorders (PVDs) are distinguished mainly based on their …

Genetic hearing loss is a common health problem with no effective therapy currently
available. DFNA15, caused by mutations of the transcription factor POU4F3, is one of the …