The review presents prenylated flavonoids as potential therapeutic agents for the treatment
of topical skin infections and wounds, as they can restore the balance in the wound …

Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …

Kurarinone, a major lavandulyl flavanone found in the roots of Sophora flavescens aiton,
has been reported to exhibit anti-inflammatory and anti-oxidative activities in …

Simple Summary Luminal A subtype breast cancer is the most prevalent form of breast
malignancy with frequent diagnosis in women. Breast cancer stem cells (BCSCs) are a rare …

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with
minimal treatment options. In the present work, Withaferin A (WA), a natural steroidal lactone …

Background Irritable bowel syndrome (IBS) is a kind of functional bowel disease that is
characterized by bellyache, abdominal distension, and diarrhea. Although not life …

Dysregulated follicular development may lead to follicular atresia, and this is associated with
oxidative stress in granulosa cells. Kurarinone is a natural compound possessing multiple …

Rutin, a natural flavonol, can modulate molecular signaling pathways and has considerable
potential in cancer treatment. However, little is known about the effect of rutin on the notch …

Sophora flavescens is a medicinal herb distributed widely in Japan and it has been used to
treat various diseases and symptoms. To explore its pharmacological use, we examined the …

Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …