Optical coherence tomography angiography offers new insights into choriocapillaris perfusion

JL Lauermann, N Eter, F Alten - Ophthalmologica, 2018 - karger.com
The choriocapillaris (CC) represents a fundamentally important vascular layer that is subject
to physiologic changes with increasing age and that is also associated with a wide range of …

DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images

SK Devalla, PK Renukanand, BK Sreedhar… - Biomedical optics …, 2018 - opg.optica.org
Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex
morphological changes with the development and progression of glaucoma, their …

Multi-scale GCN-assisted two-stage network for joint segmentation of retinal layers and discs in peripapillary OCT images

J Li, P Jin, J Zhu, H Zou, X Xu, M Tang… - Biomedical Optics …, 2021 - opg.optica.org
An accurate and automated tissue segmentation algorithm for retinal optical coherence
tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the …

Progression of photoreceptor degeneration in geographic atrophy secondary to age-related macular degeneration

M Pfau, L von der Emde, L de Sisternes… - JAMA …, 2020 - jamanetwork.com
Importance Sensitive outcome measures for disease progression are needed for treatment
trials in geographic atrophy (GA) secondary to age-related macular degeneration (AMD) …

Prevalences of segmentation errors and motion artifacts in OCT-angiography differ among retinal diseases

JL Lauermann, AK Woetzel, M Treder… - Graefe's archive for …, 2018 - Springer
Purpose To assess the prevalences of segmentation errors and motion artifacts in optical
coherence tomography angiography (OCT-A) in different retinal diseases Methods In a …

Retinal layer abnormalities as biomarkers of schizophrenia

NN Samani, FA Proudlock, V Siram… - Schizophrenia …, 2018 - academic.oup.com
Objective Schizophrenia is associated with several brain deficits, as well as visual
processing deficits, but clinically useful biomarkers are elusive. We hypothesized that retinal …

Association of complement C3 inhibitor pegcetacoplan with reduced photoreceptor degeneration beyond areas of geographic atrophy

M Pfau, S Schmitz-Valckenberg, R Ribeiro, R Safaei… - Scientific Reports, 2022 - nature.com
Preservation of photoreceptors beyond areas of retinal pigment epithelium atrophy is a
critical treatment goal in eyes with geographic atrophy (GA) to prevent vision loss. Thus, we …

Clinically verified hybrid deep learning system for retinal ganglion cells aware grading of glaucomatous progression

H Raja, T Hassan, MU Akram… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous
progression can be easily monitored by analyzing the degeneration of retinal ganglion cells …

A comprehensive review of artificial intelligence models for screening major retinal diseases

B Hassan, H Raja, T Hassan, MU Akram… - Artificial Intelligence …, 2024 - Springer
This paper provides a systematic survey of artificial intelligence (AI) models that have been
proposed over the past decade to screen retinal diseases, which can cause severe visual …

Normative data for retinal-layer thickness maps generated by spectral-domain OCT in a white population

A Invernizzi, M Pellegrini, A Acquistapace, E Benatti… - Ophthalmology …, 2018 - Elsevier
Purpose (1) To collect a dataset of normative Early Treatment Diabetic Retinopathy Study
(ETDRS) thickness map values for single retinal layers automatically segmented by …