Gene duplication is an important evolutionary mechanism allowing to provide new genetic
material and thus opportunities to acquire new gene functions for an organism, with major …

Aligning and comparing genomic sequences enables the identification of conserved
sequence signatures and can enrich for coding and noncoding functional regions. In …

Osteoporosis results from an imbalance in skeletal remodeling that favors bone resorption
over bone formation. Bone matrix is degraded by osteoclasts, which differentiate from …

Over half of all proteins are glycosylated, and alterations in glycosylation have been
observed in numerous physiological and pathological processes. Attached glycans …

Background The intestinal epithelium separates us from the microbiota but also interacts
with it and thus affects host immune status and physiology. Previous studies investigated …

Background Long considered to be the building block of life, it is now apparent that protein is
only one of many functional products generated by the eukaryotic genome. Indeed, more of …

The biology of cells of the mononuclear phagocyte system has been studied extensively in
the mouse. Studies of the pig as an experimental model have commonly been consigned to …

As a key region, promoter plays a key role in transcription regulation. A eukaryotic promoter
database called EPD has been constructed to store eukaryotic POL II promoters. Although …

Proper development and functioning of an organism depends on precise spatial and
temporal expression of all its genes. These coordinated expression-patterns are maintained …

Abstract MAGIA2 (http://gencomp. bio. unipd. it/magia2) is an update, extension and
evolution of the MAGIA web tool. It is dedicated to the integrated analysis of in silico target …