Extracellular protein components of amyloid plaques and their roles in Alzheimer's disease pathology
Alzheimer's disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ)
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …
Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host
B Singh, C Fleury, F Jalalvand… - FEMS microbiology …, 2012 - academic.oup.com
Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …
Complement in breast milk modifies offspring gut microbiota to promote infant health
D Xu, S Zhou, Y Liu, AL Scott, J Yang, F Wan - Cell, 2024 - cell.com
Breastfeeding offers demonstrable benefits to newborns and infants by providing
nourishment and immune protection and by shaping the gut commensal microbiota …
nourishment and immune protection and by shaping the gut commensal microbiota …
Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection
P Castro-Córdova, P Mora-Uribe… - Nature …, 2021 - nature.com
Clostridioides difficile spores produced during infection are important for the recurrence of
the disease. Here, we show that C. difficile spores gain entry into the intestinal mucosa via …
the disease. Here, we show that C. difficile spores gain entry into the intestinal mucosa via …
Borrelia miyamotoi: A Comprehensive Review
DW Cleveland, CC Anderson, CA Brissette - Pathogens, 2023 - mdpi.com
Borrelia miyamotoi is an emerging tick-borne pathogen in the Northern Hemisphere and is
the causative agent of Borrelia miyamotoi disease (BMD). Borrelia miyamotoi is vectored by …
the causative agent of Borrelia miyamotoi disease (BMD). Borrelia miyamotoi is vectored by …
[HTML][HTML] Offense and defense: microbial membrane vesicles play both ways
IA MacDonald, MJ Kuehn - Research in microbiology, 2012 - Elsevier
Microbes have evolved over millennia to become adapted and specialized to the
environments that they occupy. These environments may include water or soil, extreme …
environments that they occupy. These environments may include water or soil, extreme …
Mechanisms of host manipulation by Neisseria gonorrhoeae
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …
Bacteria under stress by complement and coagulation
ETM Berends, A Kuipers, MM Ravesloot… - FEMS microbiology …, 2014 - academic.oup.com
The complement and coagulation systems are two related protein cascades in plasma that
serve important roles in host defense and hemostasis, respectively. Complement activation …
serve important roles in host defense and hemostasis, respectively. Complement activation …
Human complement control and complement evasion by pathogenic microbes–tipping the balance
PF Zipfel, T Hallstroem, K Riesbeck - Molecular immunology, 2013 - Elsevier
Complement is a central homeotic system of mammals and represents the first defense line
of innate immunity. The human complement system is aimed to maintain homeostasis by …
of innate immunity. The human complement system is aimed to maintain homeostasis by …
Bacterial excretion of cytoplasmic proteins (ECP): occurrence, mechanism, and function
The excretion of cytoplasmic and signal-peptide-less proteins (ECP) by microorganisms and
eukaryotes remains a fascinating topic. In principle, it appears to be a waste of energy …
eukaryotes remains a fascinating topic. In principle, it appears to be a waste of energy …