[HTML][HTML] The impact of infection in pregnancy on placental vascular development and adverse birth outcomes

AM Weckman, M Ngai, J Wright, CR McDonald… - Frontiers in …, 2019 - frontiersin.org
Healthy fetal development is dependent on nutrient and oxygen transfer via the placenta.
Optimal growth and function of placental vasculature is therefore essential to support in …

[HTML][HTML] Poor birth outcomes in malaria in pregnancy: recent insights into mechanisms and prevention approaches

CLL Chua, W Hasang, SJ Rogerson, A Teo - Frontiers in immunology, 2021 - frontiersin.org
Pregnant women in malaria-endemic regions are susceptible to malaria in pregnancy, which
has adverse consequences on birth outcomes, including having small for gestational age …

[HTML][HTML] Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: a cohort study

RE Elphinstone, AM Weckman, CR McDonald… - PLoS …, 2019 - journals.plos.org
Background Malaria in pregnancy is associated with adverse birth outcomes. However, the
underlying mechanisms remain poorly understood. Tight regulation of angiogenic …

Prevalence and factors associated with low birth weight and preterm delivery in the ho municipality of Ghana

WK Axame, FN Binka, M Kweku - Advances in Public Health, 2022 - Wiley Online Library
Background. Low birth weight and preterm delivery are birth outcomes that can predict
newborns' survival, development, and long‐term health outcomes. This study assessed the …

[HTML][HTML] Excess risk of preterm birth with periconceptional iron supplementation in a malaria endemic area: analysis of secondary data on birth outcomes in a double …

B Brabin, S Gies, SA Roberts, S Diallo, OM Lompo… - Malaria Journal, 2019 - Springer
Background Iron supplementation before a first pregnancy may improve the future health of
mother and baby by reducing maternal anaemia. Iron supplementation could, however …

[HTML][HTML] Drugs for intermittent preventive treatment of malaria in pregnancy: Current knowledge and way forward

A Figueroa-Romero, C Pons-Duran… - Tropical Medicine and …, 2022 - mdpi.com
Malaria infection during pregnancy is an important driver of maternal and neonatal health in
endemic countries. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine …

[HTML][HTML] The relationship between markers of antenatal iron stores and birth outcomes differs by malaria prevention regimen—a prospective cohort study

HW Unger, V Laurita Longo, A Bleicher, M Ome-Kaius… - BMC medicine, 2021 - Springer
Background Iron deficiency (ID) has been associated with adverse pregnancy outcomes,
maternal anaemia, and altered susceptibility to infection. In Papua New Guinea (PNG) …

[HTML][HTML] A systematic review and meta-analysis of the effect of administration of azithromycin during pregnancy on perinatal and neonatal outcomes

M Hume-Nixon, A Quach, R Reyburn, C Nguyen… - …, 2021 - thelancet.com
Background Currently there are trials in Africa and Asia investigating whether prophylactic
azithromycin during pregnancy reduces infection-related neonatal morbidity and mortality …

[HTML][HTML] Intermittent preventive treatment with sulphadoxine-pyrimethamine but not dihydroartemisinin-piperaquine modulates the relationship between inflammatory …

K Cheng, EH Aitken, W Hasang… - PLOS Global Public …, 2024 - journals.plos.org
Women in malaria-endemic areas receive sulphadoxine-pyrimethamine (SP) as Intermittent
Preventive Treatment in Pregnancy (IPTp) to reduce malaria. While dihydroartemisinin …

Potential pharmacologic interventions targeting TLR signaling in placental malaria

FM Kobia, K Maiti, MM Obimbo, R Smith, J Gitaka - Trends in parasitology, 2022 - cell.com
Complications from placental malaria cause poor pregnancy outcomes, including low
birthweight, preterm delivery, and stillbirths. Many of these complications are driven by …