Hydroxytyrosol, tyrosol and derivatives and their potential effects on human health

A Karković Marković, J Torić, M Barbarić… - Molecules, 2019 - mdpi.com
The Mediterranean diet and olive oil as its quintessential part are almost synonymous with a
healthy way of eating and living nowadays. This kind of diet has been highly appreciated …

Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury

SJ Holditch, CN Brown, AM Lombardi… - International journal of …, 2019 - mdpi.com
Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

A comprehensive review on the anti-cancer effects of oleuropein

S Rishmawi, F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …

Comparative study on beneficial effects of hydroxytyrosol‐and oleuropein‐rich olive leaf extracts on high‐fat diet‐induced lipid metabolism disturbance and liver injury …

I Fki, S Sayadi, A Mahmoudi, I Daoued… - BioMed Research …, 2020 - Wiley Online Library
Oleuropein and hydroxytyrosol, as major compounds of olive leaves, have been reported to
exert numerous pharmacological properties, including anticancer, antidiabetic, and anti …

Anti-cancer properties of olive oil secoiridoid phenols: A systematic review of in vivo studies

R Fabiani - Food & function, 2016 - pubs.rsc.org
Epidemiological studies suggest that olive oil intake is associated to a reduced risk of
cancer. Recently, the chemopreventive activity of olive oil has been attributed to its unique …

Ethnobotanical, pharmacological, phytochemical, and clinical investigations on Moroccan medicinal plants traditionally used for the management of renal dysfunctions

B Noureddine, E Mostafa, SC Mandal - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Renal disease is a significant public health concern that
affects people all over the world. The main limitations of conventional therapy are the …

Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB …

YC Huang, MS Tsai, PC Hsieh, JH Shih… - Toxicology and applied …, 2017 - Elsevier
Cisplatin is a chemotherapeutic agent widely used in the treatment of various cancers.
However, cisplatin can induce nephrotoxicity and neurotoxicity, limiting its dosage and …

Effects of oleuropein and hydroxytyrosol on inflammatory mediators: Consequences on inflammaging

F Pojero, A Aiello, F Gervasi, C Caruso… - International Journal of …, 2022 - mdpi.com
Aging is associated with a low-grade, systemic inflammatory state defined as
“inflammaging”, ruled by the loss of proper regulation of the immune system leading to the …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …