Single‐cell technologies have revolutionized research in the last decade, including for skin
biology. Single‐cell RNA sequencing has emerged as a powerful tool allowing the …

Although several types of human skin substitutes are currently available, they usually do not
include important skin appendages such as hair follicles and sweat glands, or various skin …

On the basis of their differential location within the dermis and of discrete changes in gene
and protein expression, two major fibroblast subtypes (papillary and reticular) have …

Rosacea is a chronic inflammatory skin disorder, whose underlying cellular and molecular
mechanisms remain obscure. Here, we generate a single-cell atlas of facial skin from female …

We present an optimized dissociation protocol for preparing high-quality skin cell
suspensions for in-depth single-cell RNA-sequencing (scRNA-seq) analysis of fresh and …

Cutaneous squamous cell carcinoma (cSCC) is the second most common nonmelanoma
skin cancer characterized by high invasiveness, heterogeneity, and mainly occurs in the …

Single-cell RNA sequencing (scRNA-seq) is a novel technology that characterizes
molecular heterogeneity at the single-cell level. With the development of more automated …

Background Psoriasis is a chronically relapsing inflammatory skin disease primarily
perpetuated by skin-resident IL-17–producing T (T17) cells. Pellino-1 (Peli1) belongs to a …

Mast cells are evolutionarily old cells and the principal effectors in allergic responses and
inflammation. They are seeded from the yolk sac during embryogenesis or are derived from …

ABSTRACT A large group of keratin genes (n= 54 in the human genome) code for
intermediate filament (IF)-forming proteins and show differential regulation in epithelial cells …