Highlights•State-of-the-art in vitro enzyme cascades to assimilate CO 2-derived C1
compounds.•Current transitioning state of the biomass-based production of commodity …

The rising energy crisis and environmental problems are urging the development of more
sustainable organic synthetic methods. Photoelectrocatalytic organic synthesis (PECOS) is …

Highlights•Noncanonical redox cofactors (NRCs) can overcome the limitations of natural
cofactors.•NRCs enable specific delivery of reducing power outside of biological …

Astonishing progress has been achieved in unlocking new‐to‐nature biocatalysis in the past
decades. The progress in protein engineering enabled research to efficiently incorporate …

Great needs always motivate the birth and development of new disciplines and tools. Here
we propose in vitro BioTransformation (ivBT) as a new biomanufacturing platform, between …

The utilization of unnatural nicotinamide cofactors for reactions catalyzed by
oxidoreductases has gained increasing interest. Totally synthetic nicotinamide cofactor …

In this work, extension of the biocatalytic toolbox related to the oligomerization of C 1
synthons and novel reaction mechanisms was investigated. A synthetic enzyme cascade …