[HTML][HTML] Apolipoprotein E in lipid metabolism and neurodegenerative disease
LG Yang, ZM March, RA Stephenson… - Trends in Endocrinology & …, 2023 - cell.com
Dysregulation of lipid metabolism has emerged as a central component of many
neurodegenerative diseases. Variants of the lipid transport protein, apolipoprotein E …
neurodegenerative diseases. Variants of the lipid transport protein, apolipoprotein E …
Systematic review of dementia prevalence and incidence in United States race/ethnic populations
KM Mehta, GW Yeo - Alzheimer's & Dementia, 2017 - Elsevier
Objective To identify incidence and prevalence of dementia in racial and ethnic populations
in the United States. Methods A systematic review of literature. Results A total of 1215 …
in the United States. Methods A systematic review of literature. Results A total of 1215 …
[HTML][HTML] Alzheimer mechanisms and therapeutic strategies
There are still no effective treatments to prevent, halt, or reverse Alzheimer's disease, but
research advances over the past three decades could change this gloomy picture. Genetic …
research advances over the past three decades could change this gloomy picture. Genetic …
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Abstract The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA)
Consortium is a collaborative network of researchers working together on a range of large …
Consortium is a collaborative network of researchers working together on a range of large …
Step by step: towards a better understanding of the genetic architecture of Alzheimer's disease
JC Lambert, A Ramirez, B Grenier-Boley… - Molecular …, 2023 - nature.com
Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …
of this component has progressed over the last 10 years, thanks notably to the advent of …
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4, and the risk of late-onset Alzheimer disease in African Americans
Importance Genetic variants associated with susceptibility to late-onset Alzheimer disease
are known for individuals of European ancestry, but whether the same or different variants …
are known for individuals of European ancestry, but whether the same or different variants …
Alzheimer's disease in African Americans: risk factors and challenges for the future
LL Barnes, DA Bennett - Health affairs, 2014 - healthaffairs.org
As the US elderly population continues to expand rapidly, Alzheimer's disease poses a
major and increasing public health challenge, and older African Americans may be …
major and increasing public health challenge, and older African Americans may be …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study
K Yaffe, C Falvey, TB Harris, A Newman, S Satterfield… - Bmj, 2013 - bmj.com
Objective To examine whether observed differences in dementia rates between black and
white older people living in the community could be explained by measures of …
white older people living in the community could be explained by measures of …
Recent progress in Alzheimer's disease research, part 2: genetics and epidemiology
This is the second part of a three-part review series reviewing the most important advances
in Alzheimer's disease (AD) research since 2010. This review covers the latest research on …
in Alzheimer's disease (AD) research since 2010. This review covers the latest research on …