Periodontal disease as a possible cause for Alzheimer's disease

AR Kamer, RG Craig, R Niederman… - Periodontology …, 2020 - Wiley Online Library
Approximately 47 million people worldwide have been diagnosed with dementia, 60%‐80%
of whom have dementia of the Alzheimer's disease type. Unfortunately, there is no cure in …

Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022 - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

Periodontitis may induce gut microbiota dysbiosis via salivary microbiota

J Bao, L Li, Y Zhang, M Wang, F Chen, S Ge… - International journal of …, 2022 - nature.com
The aim of this study was to identify whether periodontitis induces gut microbiota dysbiosis
via invasion by salivary microbes. First, faecal and salivary samples were collected from …

Environmental factors and periodontal microbiome

N Buduneli - Periodontology 2000, 2021 - Wiley Online Library
Periodontal diseases are chronic inflammatory, multifactorial diseases where the major
triggering factors for disease onset are bacteria and their toxins, but the major part of tissue …

Metatranscriptomics for the human microbiome and microbial community functional profiling

Y Zhang, KN Thompson, T Branck, Y Yan… - Annual Review of …, 2021 - annualreviews.org
Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial
community gene function and regulation at scale. This review begins by summarizing the …

The progress of multi-omics technologies: determining function in lactic acid bacteria using a systems level approach

ST O'Donnell, RP Ross, C Stanton - Frontiers in microbiology, 2020 - frontiersin.org
Lactic Acid Bacteria (LAB) have long been recognized as having a significant impact
ranging from commercial to health domains. A vast amount of research has been carried out …

Functional dynamics of bacterial species in the mouse gut microbiome revealed by metagenomic and metatranscriptomic analyses

YW Chung, HJ Gwak, S Moon, M Rho, JH Ryu - PLoS One, 2020 - journals.plos.org
Background Microbial communities of the mouse gut have been extensively studied;
however, their functional roles and regulation are yet to be elucidated. Metagenomic and …

Epithelial-derived interleukin-23 promotes oral mucosal immunopathology

TS Kim, T Ikeuchi, VI Theofilou, DW Williams… - Immunity, 2024 - cell.com
At mucosal surfaces, epithelial cells provide a structural barrier and an immune defense
system. However, dysregulated epithelial responses can contribute to disease states. Here …

Cross-talk between the microbiome and chronic inflammation in esophageal cancer: potential driver of oncogenesis

T Sharma, A Gupta, R Chauhan, AA Bhat… - Cancer and Metastasis …, 2022 - Springer
Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified
at a later stage. It is one of the major causes of cancer-related deaths globally. The …

Polymicrobial interactions of oral microbiota: a historical review and current perspective

M Zhang, M Whiteley, GR Lewin - Mbio, 2022 - Am Soc Microbiol
The oral microbiota is enormously diverse, with over 700 microbial species identified across
individuals that play a vital role in the health of our mouth and our overall well-being. In …